1-cyclopropyl-7-(3,5-dimethylpiperazin-1-yl)-6,8-difluoro-4-oxoquinoline-3-carboxylic acid

Names

[ CAS No. ]:
103460-90-8

[ Name ]:
1-cyclopropyl-7-(3,5-dimethylpiperazin-1-yl)-6,8-difluoro-4-oxoquinoline-3-carboxylic acid

[Synonym ]:
amq4

Chemical & Physical Properties

[ Density]:
1.392g/cm3

[ Boiling Point ]:
565.8ºC at 760 mmHg

[ Molecular Formula ]:
C19H21F2N3O3

[ Molecular Weight ]:
377.38500

[ Flash Point ]:
296ºC

[ Exact Mass ]:
377.15500

[ PSA ]:
74.57000

[ LogP ]:
2.89320

[ Vapour Pressure ]:
1.22E-13mmHg at 25°C

[ Index of Refraction ]:
1.599

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1-Cyclopropyl-6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
  • 2,6-Dimethylpiperazin

DownStream

Related Compounds

  • 2-Methyl-6-{[1-(2,2,2-trifluoroethyl)piperidin-3-yl]methoxy}pyridine
  • N-[(1-{2-cyclopropylpyrazolo[1,5-a]pyrazin-4-yl}piperidin-4-yl)methyl]-3-methoxy-N-methylpyrazin-2-amine
  • N-{[1-(4-methanesulfonyl-1,3-benzothiazol-2-yl)piperidin-4-yl]methyl}-3-methoxy-N-methylpyrazin-2-amine
  • 3-methoxy-N-methyl-N-({1-[(oxan-2-yl)methyl]piperidin-4-yl}methyl)pyrazin-2-amine
  • 2-{4-[(Pyrimidin-2-yloxy)methyl]piperidin-1-yl}-1,3-benzoxazole
  • 4,6-Dimethyl-2-{4-[(pyrimidin-2-yloxy)methyl]piperidin-1-yl}pyrimidine
  • 5-Fluoro-2-{4-[(pyrimidin-2-yloxy)methyl]piperidin-1-yl}pyrimidine
  • 5-Chloro-2-{4-[(pyrimidin-2-yloxy)methyl]piperidin-1-yl}pyrimidine
  • 2-{[1-(5-Chloro-3-fluoropyridin-2-yl)piperidin-4-yl]methoxy}pyrimidine
  • 2-({1-[3-(Methoxymethyl)-1,2,4-thiadiazol-5-yl]piperidin-4-yl}methoxy)pyrimidine
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