2-Chloronicotinamide

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Names

[ Name ]:
2-Chloronicotinamide

[Synonym ]:
3-Pyridinecarboxamide,2-chloro
chloro-2 amido-3 pyridine
2-chloro-3-pyridinecarboxamide
2-Chloronicotinamide
chloronicotinamide
2-Chlorpyridin-3-carboxamid
2-CHLORO-PYRIDIN-3-CARBOXYLIC ACID AMIDE
3-Pyridinecarboxamide, 2-chloro-
2-CHLORONICOTINAMIDE CNAM
2-Chloropyridine-3-Carboxamide
RARECHEM AH CK 0070
EINECS 233-808-9
2-CHLORONICOTINALDEHYDE
MFCD00006237
2-chloro-nicotinic acid amide

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
313.7±27.0 °C at 760 mmHg

[ Melting Point ]:
164-167 °C(lit.)

[ Molecular Formula ]:
C₆H₅ClN₂O

[ Molecular Weight ]:
156.570

[ Flash Point ]:
143.5±23.7 °C

[ Exact Mass ]:
156.009033

[ PSA ]:
55.98000

[ LogP ]:
0.16

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.589

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

2-Chloro-3-cyanopyridine
2-Chloronicotinyl chloride
Ethyl 2-chloronicotinate
2-Chloronicotinic acid
Nicotinamide N-oxide
Nicotinamide

DownStream

2-(1-Piperazinyl)nicotinamide
2-Chlorpyridin-3-amin
2-Chlorothionicotinamide
2-Chloro-N-isobutylnicotinamide

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Effect of pyridines on phenotypic properties of Bordetella pertussis.

Infect. Immun. 38(2) , 548-53, (1982)

Several conditions of growth of Bordetella pertussis cause a reversible phenotypic alteration in properties termed modulation. Growth in medium containing nicotinic acid induces normal (X-mode) cells ...

Microwave assisted copper-free Sonogashira coupling/5-exo-dig cycloisomerization domino reaction: access to 3-(phenylmethylene) isoindolin-1-ones and related heterocycles. Hellal M and Cuny GD.

Tetrahedron Lett. 52(42) , 5508-11, (2011)

Benzyl and tert Butyl Sulfoxides as Sulfenyl Halide Equivalents: a Convenient Preparation of Benzisothiazolones. Wright SW, et al.

Tetrahedron Lett. 33 , 153-6, (1992)

N-Allyl-2-chloronicotinamide
5-Bromo-2-chloronicotinamide
N-Benzyl-2-chloronicotinamide
N-methyl-2-chloronicotinamide
N-phenyl-2-chloronicotinamide
6-methyl-2-chloronicotinamide