3-(2,5-dimethylphenyl)-2-methylquinazolin-4-one
Names
[ CAS No. ]:
10367-31-4
[ Name ]:
3-(2,5-dimethylphenyl)-2-methylquinazolin-4-one
[Synonym ]:
3-<2.5-Dimethyl-phenyl>-2-methyl-3H-chinazolin-4-on
Ro 326
Chemical & Physical Properties
[ Density]:
1.14g/cm3
[ Boiling Point ]:
433.2ºC at 760 mmHg
[ Molecular Formula ]:
C17H16N2O
[ Molecular Weight ]:
264.32200
[ Flash Point ]:
215.8ºC
[ Exact Mass ]:
264.12600
[ PSA ]:
34.89000
[ LogP ]:
3.31090
[ Vapour Pressure ]:
1.04E-07mmHg at 25°C
[ Index of Refraction ]:
1.614
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- VA4146600
- CHEMICAL NAME :
- 4(3H)-Quinazolinone, 2-methyl-3-(2,5-xylyl)-
- CAS REGISTRY NUMBER :
- 10367-31-4
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C17-H16-N2-O
- MOLECULAR WEIGHT :
- 264.35
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >1200 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
- REFERENCE :
- THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 22,129,1967
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 710 mg/kg
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - convulsions or effect on seizure threshold Behavioral - excitement
- REFERENCE :
- PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 17,616,1962
Safety Information
[ HS Code ]:
2933990090
Customs
[ HS Code ]: 2933990090
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%