6H-Pyrido[4,3-b]carbazole,9-methoxy-5,11-dimethyl-

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Names

[ CAS No. ]:
10371-86-5

[ Name ]:
6H-Pyrido[4,3-b]carbazole,9-methoxy-5,11-dimethyl-

[Synonym ]:
9-Methoxyellipticine
9-methoxyellipcitine
Ellipticine,9-methoxy

Chemical & Physical Properties

[ Density]:
1.256g/cm3

[ Boiling Point ]:
524.7ºC at 760mmHg

[ Molecular Formula ]:
C18H16N2O

[ Molecular Weight ]:
276.33200

[ Flash Point ]:
168.4ºC

[ Exact Mass ]:
276.12600

[ PSA ]:
37.91000

[ LogP ]:
4.49470

[ Vapour Pressure ]:
1.41E-10mmHg at 25°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UU8840000
CHEMICAL NAME :
6H-Pyrido(4,3-b)carbazole, 5,11-dimethyl-9-methoxy-
CAS REGISTRY NUMBER :
10371-86-5
BEILSTEIN REFERENCE NO. :
0279742
LAST UPDATED :
199612
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C18-H16-N2-O
MOLECULAR WEIGHT :
276.36
WISWESSER LINE NOTATION :
T D6 B656 FN LMJ C1 J1 PO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
150 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Mutation in mammalian somatic cells
TEST SYSTEM :
Rodent - hamster Ovary
DOSE/DURATION :
100 ug/L
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 43,3544,1983

Safety Information

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-Methoxy-2-nitroaniline
  • 6-bromo-4,7-dimethyl-2,3-dihydroinden-1-one
  • 1,4-Dibromo-2,5-dimethylbenzene

DownStream

  • 6H-Pyrido[4,3-b]carbazole,9-methoxy-5,6,11-trimethyl-
  • 5,11-dimethylpyrido[4,3-b]carbazol-9-one
  • Methanol
  • nsc331811
  • 9-hydroxyellipticine

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 9-methoxy-5,11-dimethyl-6-(3-methylbutyl)pyrido[4,3-b]carbazole
  • 2,6-dihydro-9-methoxy-5,11-dimethyl-1H-pyrido[4,3-b]carbazol-1-one
  • 1-(amino-3-propylamino)-5,11-dimethyl-9-methoxy-6H-pyrido(4,3-b)carbazole
  • N-[3-(Ethylamino)propyl]-5,11-dimethyl-9-methoxy-6H-pyrido[4,3-b]carbazole-1-amine
  • acetic anhydride (1,1'-13c2)
  • 6H-Pyrido[4,3-b]carbazole,9-methoxy-5,6,11-trimethyl-