CHALCONE, 2-(2-DIMETHYLAMINOETHOXY)-, CITRATE

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Names

[ CAS No. ]:
103734-52-7

[ Name ]:
CHALCONE, 2-(2-DIMETHYLAMINOETHOXY)-, CITRATE

Chemical & Physical Properties

[ Boiling Point ]:
452.2ºC at 760mmHg

[ Molecular Formula ]:
C₂₅H₂₉NO₉

[ Molecular Weight ]:
487.49900

[ Flash Point ]:
227.3ºC

[ Exact Mass ]:
487.18400

[ PSA ]:
161.67000

[ LogP ]:
2.13210

[ Vapour Pressure ]:
2.28E-08mmHg at 25°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: FL7026000

CHEMICAL NAME :: Chalcone, 2-(2-dimethylaminoethoxy)-, citrate

CAS REGISTRY NUMBER :: 103734-52-7

LAST UPDATED :: 198806

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C19-H21-N-O2.C6-H8-O7

MOLECULAR WEIGHT :: 487.55

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 603 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia

REFERENCE :: JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 47,640,1958

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 158 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia

REFERENCE :: JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 47,640,1958

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 40800 ug/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia

REFERENCE :: JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 47,640,1958

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 41 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia

REFERENCE :: JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 47,640,1958

Related Compounds

1-[2-(2-dimethylaminoethoxy)phenyl]ethanone
9,10-Dihydro-11-(2-(2-dimethylaminoethoxy)ethyl)-9,10-ethanoanthracene hydrochloride
2-(2-Dimethylaminoethoxy)bibenzyl hydrochloride
2-[(2-dimethylaminoethoxy-dimethyl-silyl)methyl-dimethyl-silyl]oxy-N,N-dimethyl-ethanamine
2-(2-dimethylaminoethoxy)-N,N-dimethyl-ethanamine: 3-dimethylaminoprop anenitrile
2-(2-dimethylaminoethoxy)-N,N-dimethyl-ethanamine