Fasudil

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Names

[ CAS No. ]:
103745-39-7

[ Name ]:
Fasudil

[Synonym ]:
Fasudilum [inn-latin]
H-1077 dihydrochloride
1-(5-Isoquinolinesulfonyl)-1H-hexahydro-1,4-diazepine,Dihydrochloride
1-(5-ISOQUINOLINE-SULFONYL)-HOMOPIPERAZINE
HA 1077,DIHYDROCHLORIDE
5-(1,4-Diazepan-1-ylsulfonyl)isoquinoline
HA-1077 DIHYDROCHLORIDE NOVEL VASODILATO R AGE
Isoquinoline, 5-[(hexahydro-1H-1,4-diazepin-1-yl)sulfonyl]-
at877
5-(1,4-DIAZEPAN-1-SULFONYL)ISOQUINOLINE
Fasudilum
1-(5-Isoquinolinylsulfonyl)homopiperazine
Fasudil
MFCD00866182
hexahydro-1-(5-isoquinolinylsulfonyl)-1H-1,4-diazepine
1-(5-isoquinolinesulphonyl)-homopiperazine
1-(5-Isoquinolinesulphonyl)homopiperazine
N-(5-Isoquinolinesulfonyl)-1,4-perhydrodiazepine
(5-ISOQUINOLINESULFONYL)HOMOPIPERAZINE

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
506.2±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C14H17N3O2S

[ Molecular Weight ]:
291.37

[ Flash Point ]:
259.9±32.9 °C

[ PSA ]:
70.68000

[ LogP ]:
1.19

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.622

[ Storage condition ]:
Store at RT

[ Water Solubility ]:
H2O: >200 mg/mL

Safety Information

[ WGK Germany ]:
3

[ RTECS ]:
HM4031166

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Homopiperazine
  • ISOQUINOLINE-5-SULFONYL CHLORIDE
  • Isoquinoline-5-sulfonyl chloride hydrochloride

DownStream

  • Fasudil Hydrochloride

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • Fasudil HCl
  • Fasudil dimer
  • HYDROXYFASUDIL
  • Hydroxyfasudil
  • Fasudil iMpurity
  • Fasudil Impurity 8
  • 5-Methyl-1-(phenylsulfonyl)-5,6-dihydrocyclopenta[B]pyrrol-4(1H)-one
  • Ethyl 6-ethylpiperidine-3-carboxylate
  • Ethyl 4-amino-5-fluoro-2-methylbenzoate
  • 7-[(4-hydroxy-6-methylpyrimidin-2-yl)amino]-2-methylpyrido[3,4-e][1,2,4]triazolo[1,5-a]pyrimidin-6(7H)-one
  • 1,2,4,4-Tetramethylcyclopentane-1-carboxylic acid
  • 6-Chloro-2-(tetrahydrofuran-2-yl)pyrimidin-4(3H)-one
  • 1-Cyclobutoxy-4-ethynyl-2-methylbenzene
  • 2,2-Difluoro-1-(quinolin-2-yl)ethan-1-one
  • 2-{1-[(Tert-butoxy)carbonyl]pyrrolidin-3-yl}-4-(propan-2-yl)-1,3-oxazole-5-carboxylic acid
  • 4-[(Piperidin-3-yl)methyl]benzene-1,2,3-triol
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