2'-Deoxy-2'-fluoroguanosine

Suppliers

Names

[ CAS No. ]:
103884-98-6

[ Name ]:
2'-Deoxy-2'-fluoroguanosine

[Synonym ]:
6H-Purin-6-one, 2-amino-9-(2-deoxy-2-fluoro-D-arabinofuranosyl)-1,9-dihydro-
2-Amino-9-(2-deoxy-2-fluoro-D-arabinofuranosyl)-1,9-dihydro-6H-purin-6-one
2'-Deoxy-2'-fluoroguanosine
Guanosine, 2'-deoxy-2'-fluoro-

Chemical & Physical Properties

[ Density]:
2.2±0.1 g/cm3

[ Boiling Point ]:
726.1ºC

[ Molecular Formula ]:
C10H12FN5O4

[ Molecular Weight ]:
285.23

[ Flash Point ]:
392.9ºC

[ Exact Mass ]:
285.087341

[ PSA ]:
139.28000

[ LogP ]:
-0.53

[ Vapour Pressure ]:
3.94E-22mmHg at 25°C

[ Index of Refraction ]:
1.876

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UP0789000
CHEMICAL NAME :
6H-Purin-6-one, 2-amino-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)- 1,9-dihydro-
CAS REGISTRY NUMBER :
103884-98-6
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C10-H12-F-N5-O4
MOLECULAR WEIGHT :
285.27

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
DNA inhibition
TEST SYSTEM :
Rodent - mouse Leukocyte
DOSE/DURATION :
50 umol/L
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 29,2389,1986

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-Amino-6-chloropurine-9-beta-D-(2'-deoxy-3',5'-di-O-benzoyl-2'-fluoro)arabinoriboside
  • 2,6-Dichloropurine
  • 1,3-di-O-acetyl-5-O-benzoyl-2-deoxy-2-fluoro-D-arabinofuranosyl bromide
  • 9H-Purine, 9-(3-O-acetyl-5-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl)-2,6-dichloro-
  • 2,6-diazido-9-(3-O-acetyl-5-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purine
  • 9-(3-O-acetyl-5-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl)-2-acetamido-6-chloropurine
  • 2-Deoxy-2-fluoro-alpha-D-arabinofuranosyl bromide 3,5-dibenzoate
  • 6-Chloro-9,N-bis(trimethylsilyl)-9H-purin-2-amine
  • 9-(3-O-acetyl-5-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purine-2,6-diamine

DownStream

Related Compounds

  • 2'-Deoxy-2'-fluoroguanosine
  • 2'-Deoxy-2'-fluoroguanosine
  • N2-isobutyryl-2'-deoxy-2'-fluoroguanosine
  • 3',5'-O-Diacetyl-6-chloro-2'-deoxy-2'-fluoroguanosine
  • N2-isobutyryl-3'-O,5'-O-bis(tetrahydrofuranyl)-2'-deoxy-2'-fluoroguanosine
  • 2'-Deoxy-2'-[(trifluoroacetyl)amino]guanosine
  • 6-hydroxy-N-((2-isopropoxypyridin-3-yl)methyl)pyrimidine-4-carboxamide
  • N-((6-ethoxypyridin-3-yl)methyl)-6-hydroxypyrimidine-4-carboxamide
  • N-(2-(4-fluorophenoxy)ethyl)-6-hydroxypyrimidine-4-carboxamide
  • 6-hydroxy-N-(2-(thiophen-2-yl)imidazo[1,2-a]pyridin-3-yl)pyrimidine-4-carboxamide
  • 6-hydroxy-N-(2-(6-oxo-4-phenylpyrimidin-1(6H)-yl)ethyl)pyrimidine-4-carboxamide
  • N-((2-(2-chlorophenyl)-4-methylthiazol-5-yl)methyl)-6-hydroxypyrimidine-4-carboxamide
  • (E)-3-(furan-2-yl)-N-((3-(2-oxo-1,2-dihydropyridin-3-yl)-1,2,4-oxadiazol-5-yl)methyl)acrylamide
  • 2,6-difluoro-N-((3-(2-oxo-1,2-dihydropyridin-3-yl)-1,2,4-oxadiazol-5-yl)methyl)benzamide
  • 6-Hydroxythiochroman-4-one 1,1-dioxide
  • 2-(2-fluorophenoxy)-N-((3-(2-oxo-1,2-dihydropyridin-3-yl)-1,2,4-oxadiazol-5-yl)methyl)acetamide
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.