MK-4827(Niraparib)

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Names

[ CAS No. ]:
1038915-60-4

[ Name ]:
MK-4827(Niraparib)

[Synonym ]:
pound notMK4827 pound not MK 4827
2H-Indazole-7-carboxamide, 2-[4-[(3S)-3-piperidinyl]phenyl]-
2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide
Niraparib
MK4827
2-{4-[(3S)-3-Piperidinyl]phenyl}-2H-indazole-7-carboxamide
UNII:HMC2H89N35
MK-4827

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
463.6±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C19H20N4O

[ Molecular Weight ]:
320.388

[ Flash Point ]:
234.2±28.7 °C

[ Exact Mass ]:
320.163696

[ PSA ]:
73.93000

[ LogP ]:
2.85

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.705

[ Storage condition ]:
-20°C

Safety Information

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 3-{4-[7-(aminocarbonyl)-2H-indazol-2-yl]phenyl}piperidinium chloride

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • Niraparib hydrochloride
  • MK-4827 tosylate
  • MK-4827 (R-enantiomer)
  • MK-8998
  • MK-8745
  • MK-0812 Succinate
  • (2R,3R)-2-(1-Methylimidazol-2-yl)oxolan-3-amine;dihydrochloride
  • (2S,3R)-2-(1,3,5-Trimethylpyrazol-4-yl)oxolan-3-amine;dihydrochloride
  • (2S,3R)-2-Pyridin-4-yloxolan-3-amine;dihydrochloride
  • rac-(1R,2S)-2-(1H-1,2,4-triazol-1-yl)cyclohexane-1-carboxylic acid hydrochloride, cis
  • 3-(Methylamino)cyclobutane-1-carboxamide;hydrochloride
  • rel-(3R,4R)-4-(2,3-dihydro-1H-isoindol-2-yl)pyrrolidin-3-ol dihydrochloride
  • (E)-1-(5-amino-1,1,1-trifluoropentan-2-ylidene)-2-phenylhydrazine hydrochloride
  • rac-(3R,4R)-4-[(1-methyl-1H-pyrazol-4-yl)oxy]oxolan-3-amine dihydrochloride
  • (3R,4S)-N,N-Dimethyl-4-(triazol-1-yl)pyrrolidin-3-amine;trihydrochloride
  • [(2R,3S)-2-(1H-Pyrazol-4-yl)oxan-3-yl]methanamine;dihydrochloride
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