10H-Phenothiazine-10-propanamine,N,N-dimethyl-2-(methylthio)-

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Names

[ CAS No. ]:
1039-59-4

[ Name ]:
10H-Phenothiazine-10-propanamine,N,N-dimethyl-2-(methylthio)-

[Synonym ]:
Thiomethylpromazine
N-<3-Dimethylamino-propyl>-2-methylmercapto-phenothiazin
TZ 11

Chemical & Physical Properties

[ Density]:
1.22g/cm3

[ Boiling Point ]:
474.6ºC at 760 mmHg

[ Molecular Formula ]:
C₁₈H₂₂N₂S₂

[ Molecular Weight ]:
330.51100

[ Flash Point ]:
240.9ºC

[ Exact Mass ]:
330.12200

[ PSA ]:
57.08000

[ LogP ]:
5.02790

[ Vapour Pressure ]:
3.55E-09mmHg at 25°C

[ Index of Refraction ]:
1.673

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SO8050000

CHEMICAL NAME :: Phenothiazine, 10-(3-dimethylaminopropyl)-2-methylthio-

CAS REGISTRY NUMBER :: 1039-59-4

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C18-H22-N2-S2

MOLECULAR WEIGHT :: 330.54

WISWESSER LINE NOTATION :: T C666 BN ISJ B3N1&1 ES1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1450 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,51,1972

Safety Information

[ HS Code ]:
2934300000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

2-Methylthiophenothiazine
3-Chloro-N,N-dimethylpropan-1-amine

DownStream

Customs

[ HS Code ]: 2934300000

[ Summary ]:
2934300000. other compounds containing in the structure a phenothiazine ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%