1-(2-dimethylaminoethyl)-4-methylpiperazine

Suppliers

Names

[ CAS No. ]:
104-19-8

[ Name ]:
1-(2-dimethylaminoethyl)-4-methylpiperazine

[Synonym ]:
Piperazine, 1-[2- (dimethylamino)ethyl]-4-methyl-
Kaolizer 8
N-Methyl-N'-(β-dimethylaminoethyl)piperazine
1-Piperazineethanamine,N,N,4-trimethyl
N,N,4-trimethyl-1-piperazineethanamine
EINECS 203-183-7
1-(2-DIMETHYLAMINOETHYL)-4-METHYLPIPERAZINE
1-[2-(Dimethylamino)ethyl]-4-methylpiperazine
N,N-Dimethyl-2-(4-methylpiperazin-1-yl)ethanamine
MFCD00059773
N,N-Dimethyl-2-(4-methyl-1-piperazinyl)ethanamine
1-Piperazineethanamine, N,N,4-trimethyl-
Toyocat NP

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
207.5±8.0 °C at 760 mmHg

[ Molecular Formula ]:
C9H21N3

[ Molecular Weight ]:
171.283

[ Flash Point ]:
74.5±9.0 °C

[ Exact Mass ]:
171.173553

[ PSA ]:
9.72000

[ LogP ]:
-0.45

[ Vapour Pressure ]:
0.2±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.476

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TL6125000
CHEMICAL NAME :
Piperazine, 1-(2-(dimethylamino)ethyl)-4-methyl-
CAS REGISTRY NUMBER :
104-19-8
BEILSTEIN REFERENCE NO. :
0106624
LAST UPDATED :
199709
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C9-H21-N3
MOLECULAR WEIGHT :
171.33
WISWESSER LINE NOTATION :
T6N DNTJ A2N1&1 D1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Open irritation test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,867,1986
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,867,1986 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1420 uL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
390 uL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962

Safety Information

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36/37/39

[ RIDADR ]:
2922

[ RTECS ]:
TL6125000

[ Packaging Group ]:
II

[ Hazard Class ]:
8

[ HS Code ]:
2933599090

Synthetic Route

Precursor & DownStream

Precursor

  • TMEDA
  • α-Aminoisobutyronitrile
  • Chlormethine hydrochloride
  • Trichlormethine (hydrochloride)
  • Dimethylamine
  • methylpiperazine
  • (2-Chloroethyl)dimethylamine hydrochloride
  • ethyl 4-methylpiperazine-1-carboxylate
  • Formaldehyde
  • Methanol

DownStream

Customs

[ HS Code ]: 2933599090

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%


Related Compounds

  • 2,5-Dimethyl-1-(2-dimethylaminoethyl)-4-phenyl-4-propionyloxypiperidine
  • 1-(2-Bromobutanoyl)-4-Methylpiperazine
  • 1-(2-bromophenyl)-4-methylpiperazine
  • 1-(2-Bromoethyl)-4-methylpiperazine Dihydrobromide
  • 1-(2-IODOBENZYL)-4-METHYLPIPERAZINE
  • 1-(2-Chloroethyl)-4-methylpiperazine hydrochloride