5-Ethyl-2-methylpyridine

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Names

[ CAS No. ]:
104-90-5

[ Name ]:
5-Ethyl-2-methylpyridine

[Synonym ]:
2-Picoline,5-ethyl
Aldehydecollidine
5-ethyl-2-methyl-pyridine
Aldehydine
5-Ethyl-2-picoline
Ethyl-5 methyl-2 pyridine
Pyridine, 5-ethyl-2-methyl-
Aldehydkollidin
2-METHYL-5-ETHYLPYRIDINE
MFCD00006344
EINECS 203-250-0
3-Ethyl-6-methylpyridine
T6NJ B1 E2
5-Ethyl-2-methylpyridine
Pyridine,5-ethyl-2-methyl
5-ETHYL-2-METHYL PYRIDINE(MEP)

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
176.0±9.0 °C at 760 mmHg

[ Melting Point ]:
-70.9 °C

[ Molecular Formula ]:
C₈H₁₁N

[ Molecular Weight ]:
121.180

[ Flash Point ]:
66.1±0.0 °C

[ Exact Mass ]:
121.089149

[ PSA ]:
12.89000

[ LogP ]:
2.18

[ Vapour density ]:
4.2 (vs air)

[ Vapour Pressure ]:
1.5±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.500

[ Stability ]:
Stable. Hygroscopic. Combustible. Incompatible with strong oxidizing agents.

[ Water Solubility ]:
practically insoluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TJ6825000

CHEMICAL NAME :: 2-Picoline, 5-ethyl-

CAS REGISTRY NUMBER :: 104-90-5

BEILSTEIN REFERENCE NO. :: 0109269

LAST UPDATED :: 199806

DATA ITEMS CITED :: 13

MOLECULAR FORMULA :: C8-H11-N

MOLECULAR WEIGHT :: 121.20

WISWESSER LINE NOTATION :: T6NJ B1 E2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Open irritation test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 368 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1000 ppm/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 826 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 282 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 294 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 1 mL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 2500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Sex chromosome loss and nondisjunction

TEST SYSTEM :: Yeast - Saccharomyces cerevisiae

DOSE/DURATION :: 1500 ppm

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 163,23,1986 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 2 mg/m3;Skin JAN 1993

Safety Information

[ Symbol ]:

GHS05, GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H311 + H331-H314

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
C:Corrosive

[ Risk Phrases ]:
R20/21/22;R34

[ Safety Phrases ]:
S26-S36/37/39-S45-S61

[ RIDADR ]:
UN 2300 6.1/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
TJ6825000

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
2942000000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Acetylene
5-ethyl-2-methyl-1-oxido-pyridine
paraldehyde
Aminoform
Methyl Vinyl Ether
2-Ethyl-2-hexenal
Benzaldehyde
Butyraldehyde
2-Fluorobenzaldehyde
Ethane, 1,1-dichloro-

DownStream

2,4,6-Trichloropyrimidine
Pyridine
2-picoline
3-Ethylpyridine
3-Mepy
2,5-Lutidine
Methyl 6-methylnicotinate
6-Methylnicotinic acid
5-ETHYLPYRIDINE-2-CARBOXYLIC ACID
2,5-Pyridinedicarboxylic acid

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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