Eprazinone

Names

[ CAS No. ]:
10402-90-1

[ Name ]:
Eprazinone

[Synonym ]:
3-[4-(2-Ethoxy-2-phenylethyl)piperazin-1-yl]-2-methyl-1-phenylpropan-1-one
3-[4-(2-Ethoxy-2-phenylethyl)-1-piperazinyl]-2-methyl-1-phenyl-1-propanone
Mucitux
Eftapan
EINECS 233-873-3
Resplen
Eprazinone
1-Propanone, 3-[4-(2-ethoxy-2-phenylethyl)-1-piperazinyl]-2-methyl-1-phenyl-
746 CE
MFCD00866843
3-(4-(2-Ethoxy-2-phenylethyl)piperazin-1-yl)-2-methyl-1-phenylpropan-1-one

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
503.9±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C24H32N2O2

[ Molecular Weight ]:
380.523

[ Flash Point ]:
258.5±30.1 °C

[ Exact Mass ]:
380.246368

[ PSA ]:
32.78000

[ LogP ]:
3.58

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.550

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UH1599000
CHEMICAL NAME :
Propiophenone, 2-(4-(beta-ethoxyphenethyl)-1-piperazinyl)methyl-
CAS REGISTRY NUMBER :
10402-90-1
BEILSTEIN REFERENCE NO. :
0844684
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C24-H32-N2-O2
MOLECULAR WEIGHT :
380.58
WISWESSER LINE NOTATION :
T6N DNTJ A1YR&O2 D1Y1&VR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
111 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 2,314,1968
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
246 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 2,314,1968

Safety Information

[ HS Code ]:
2933599090

Synthetic Route

Precursor & DownStream

Precursor

  • 1-(2-Ethoxy-2-phenylethyl)piperazine dihydrochloride
  • Phenyl ethyl ketone

DownStream

Customs

[ HS Code ]: 2933599090

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%


Related Compounds

  • Eprazinone
  • Eprazinone 2HCl