Zolantidine dimaleate

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Names

[ Name ]:
Zolantidine dimaleate

[Synonym ]:
2-Benzothiazolamine, N-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]-, (2Z)-2-butenedioate (1:2)
AL1YII70LM
Zolantidine dimaleate
N-{3-[3-(Piperidin-1-ylmethyl)phenoxy]propyl}-1,3-benzothiazol-2-amine (2Z)-but-2-enedioate (1:2)
N-[3-[3-(1-Piperidinylmethyl)phenoxy]propyl]-2-benzothiazolamine dimaleate
SKF 95282 dimaleate
SKF-95282 dimaleate salt
N-{3-[3-(1-Piperidinylmethyl)phenoxy]propyl}-1,3-benzothiazol-2-amine (2Z)-2-butenedioate (1:2)

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₀H₃₅N₃O₉S

[ Molecular Weight ]:
613.68

[ Exact Mass ]:
613.209412

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Zolantidine (SK&F 95282) is a potent selective brain-penetrating histamine H2-receptor antagonist.

Br. J. Pharmacol. 93(1) , 69-78, (1988)

1. The novel benzthiazole derivative zolantidine (SK&F 95282) is a potent antagonist of histamine at H2-receptors in guinea-pig atrium and rat uterus. Only apparent pA2 values of 7.46 and 7.26 respect...

Linking solubility and permeability assays for maximum throughput and reproducibility.

J. Biomol. Screen. 10(4) , 383-90, (2005)

Solubility and permeability are intimately linked in drug absorption processes. They have, however, been traditionally assayed separately. To support this linkage, a combined solubility/permeability a...

Identification of novel functional inhibitors of acid sphingomyelinase.

PLoS ONE 6 , e23852, (2011)

We describe a hitherto unknown feature for 27 small drug-like molecules, namely functional inhibition of acid sphingomyelinase (ASM). These entities named FIASMAs (Functional Inhibitors of Acid Sphing...

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(2,4-Difluorophenyl)(4-(((5,6,7,8-tetrahydrocinnolin-3-yl)oxy)methyl)piperidin-1-yl)methanone
N-(1-(3-(tert-butyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)azetidin-3-yl)-N,2-dimethylpropane-1-sulfonamide
N-(2-chlorophenyl)-3-oxo-4-(1,3-thiazol-2-yl)piperazine-1-carboxamide
4-((4-(Tetrahydrofuran-3-yl)-1,4-diazepan-1-yl)sulfonyl)benzo[c][1,2,5]thiadiazole
(1R,5S)-8-((4-methoxyphenyl)sulfonyl)-3-(1H-pyrazol-1-yl)-8-azabicyclo[3.2.1]octane
N-(1-(3-(tert-butyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)azetidin-3-yl)-3,3,3-trifluoro-N-methylpropane-1-sulfonamide

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