nalorphine hydrobromide

Names

[ CAS No. ]:
1041-90-3

[ Name ]:
nalorphine hydrobromide

[Synonym ]:
N-Allylnormorphine hydrobromide
Nalorphine hydrobromide
C19H21NO3.HBr
Nalorphine bromide
EINECS 213-868-2

Chemical & Physical Properties

[ Boiling Point ]:
493.6ºC at 760mmHg

[ Melting Point ]:
208ºC

[ Molecular Formula ]:
C19H22BrNO3

[ Molecular Weight ]:
392.28700

[ Flash Point ]:
252.3ºC

[ Exact Mass ]:
391.07800

[ PSA ]:
52.93000

[ LogP ]:
2.65030

[ Vapour Pressure ]:
1.46E-10mmHg at 25°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QC7705000
CHEMICAL NAME :
Morphinan-3,6-alpha-diol, 17-allyl-7,8-didehydro-4,5-alpha-epoxy-, hydrobromide
CAS REGISTRY NUMBER :
1041-90-3
LAST UPDATED :
199512
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C19-H21-N-O3.Br-H
MOLECULAR WEIGHT :
392.33

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
260 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - other changes
REFERENCE :
NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 51,199,1955
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
921 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 21,668,1969

Related Compounds

  • nalorphine
  • Nalorphine epoxide
  • nalorphine hydrochloride ciii (250 mg)
  • Xylopropamine Hydrobromide
  • Scopolamine hydrobromide
  • Vortioxetine hydrobromide Impurity 09
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • N-{1-[6-(trifluoromethyl)pyrimidin-4-yl]pyrrolidin-3-yl}acetamide
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 3-Cyclopropyl-1-(1-{2-[(4-fluorophenyl)sulfanyl]acetyl}piperidin-4-yl)imidazolidine-2,4-dione
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 3-(2,3-Dihydro-1-benzofuran-5-yl)-1-(5-fluoro-2-methoxybenzenesulfonyl)pyrrolidine
  • 3-{[1-(5-Bromofuran-2-carbonyl)pyrrolidin-3-yl]oxy}-1,2,5-thiadiazole