1H-Pyrano3,4:6,7indolizino1,2-bquinoline-3,14(4H,12H)-dione, 9-amino-4-ethyl-4-hydroxy-

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Names

[ CAS No. ]:
104195-62-2

[ Name ]:
1H-Pyrano3,4:6,7indolizino1,2-bquinoline-3,14(4H,12H)-dione, 9-amino-4-ethyl-4-hydroxy-

[Synonym ]:
10-amino-CPT
Camptothecin,10-amino

Chemical & Physical Properties

[ Density]:
1.55g/cm3

[ Boiling Point ]:
825.9ºC at 760mmHg

[ Molecular Formula ]:
C20H17N3O4

[ Molecular Weight ]:
363.36700

[ Flash Point ]:
453.3ºC

[ Exact Mass ]:
363.12200

[ PSA ]:
107.44000

[ LogP ]:
2.24300

[ Vapour Pressure ]:
6.86E-29mmHg at 25°C

[ Index of Refraction ]:
1.771

Synthetic Route

Precursor & DownStream

Precursor

  • RUBITECAN
  • Benzaldehyde,2-amino-5-nitro-
  • (±)- 1H-Pyrano[3,4-f]indolizine-3,6,10(4H)-trione, 4-ethyl-7,8-dihydro-4-hydroxy

DownStream

  • Campathecin