2-Chloromandelic acid

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Names

[ CAS No. ]:
10421-85-9

[ Name ]:
2-Chloromandelic acid

[Synonym ]:
2-Chloromandelic acid
QVYQR BG
2-Chloro-α-hydroxybenzeneacetic acid
EINECS 233-900-9
(±)-2-Chloro-α-hydroxyphenylacetic acid
2-Chloro-DL-mandelic acid
MFCD00084962
Benzeneacetic acid, 2-chloro-α-hydroxy-
(2-Chlorophenyl)glycolic acid
(2-Chlorophenyl)-hydroxy-acetic acid
DL-2-Chloromandelic acid
2-(2-Chlorophenyl)-2-hydroxyacetic acid
(2-Chlorophenyl)(hydroxy)acetic acid

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
350.3±27.0 °C at 760 mmHg

[ Melting Point ]:
80-85ºC

[ Molecular Formula ]:
C8H7ClO3

[ Molecular Weight ]:
186.592

[ Flash Point ]:
165.7±23.7 °C

[ Exact Mass ]:
186.008377

[ PSA ]:
57.53000

[ LogP ]:
1.52

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.606

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2918199090

Precursor & DownStream

Precursor

  • 2-(2-chlorophenyl)-2-hydroxyacetonitrile
  • o-Chloroacetophenone
  • Chloroform
  • 2-Chlorobenzaldehyde
  • HYDROGEN CYANIDE
  • Bromoform
  • 2-Chlorobenzoic acid
  • 3,4-Furandiol,2-(2-chlorophenyl)-2,5-dihydro-5-imino-

DownStream

  • (S)-2-CARBOXYMETHYL-PIPERIDINE-1-CARBOXYLICACIDTERT-BUTYLESTER
  • 2-Chlorobenzaldehyde
  • 2-Chlorobenzoic acid
  • Methyl 2-bromo-2-(2-chlorophenyl)acetate
  • Methyl chloro(2-chlorophenyl)acetate
  • ETHYL 2-CHLOROBENZOYLFORMATE
  • 2-Chlorophenylaceticacid
  • 2-ChloroMandelic Acid Methyl Ester
  • 2-(2-chlorophenyl)-2-(4-chlorophenyl)acetic acid
  • 2-Bromo-2-(2-chlorophenyl)acetic acid

Customs

[ HS Code ]: 2918199090

[ Summary ]:
2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

QSAR-based solubility model for drug-like compounds.

Bioorg. Med. Chem. 18 , 7078-84, (2010)

Solubility plays a very important role in the selection of compounds for drug screening. In this context, a QSAR model was developed for predicting water solubility of drug-like compounds. First, a se...

Modeling the retention mechanism for high-performance liquid chromatography with a chiral ligand mobile phase and enantioseparation of mandelic acid derivatives.

J. Sep. Sci. 38 , 2085-92, (2015)

The chromatographic retention mechanism describing relationship between retention factor and concentration of Cu(2+) (l-phenylalanine)2 using chiral ligand mobile phase was investigated and eight mand...

Resolution of 2-chloromandelic acid with (R)-(+)-N-benzyl-1-phenylethylamine: chiral discrimination mechanism.

Chirality 24(5) , 349-55, (2012)

During the resolution of 2-chloromandelic acid with (R)-(+)-N-benzyl-1-phenylethylamine, the crystals of the less soluble salt were grown, and their structure were determined and presented. The chiral...


More Articles


Related Compounds

  • 2-chloromandelic acid
  • (S)-2-Chloromandelic acid
  • 2-ChloroMandelic Acid Methyl Ester
  • (S)-2-ChloroMandelic Acid Ethyl Ester
  • (R)-2-Chloromandelic Acid Ethyl Ester
  • (R)-(-)-2-METHYL-2,4-PENTANEDIOL