PF-00299804

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Names

[ CAS No. ]:
1042385-75-0

[ Name ]:
PF-00299804

[Synonym ]:
(2E)-N-{4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl}-4-(1-piperidinyl)-2-butenamide hydrate (1:1)
Dacomitinib [USAN:INN]
2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-4-(1-piperidinyl)-, (2E)-, hydrate (1:1)
(2E)-N-[4-[(3-chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-4-(1-piperidinyl)-2-butenamide, hydrate (1:1)
UNII-5092U85G58
2-Butenamide,N-(4-((3-chloro-4-fluorophenyl)amino)-7-methoxy-6-quinazolinyl)-4-(1-piperidinyl)-,hydrate (1:1),(2E)
Dacomitinib
dacomitinib hydrate
Dacomitinib hydrate (JAN)
(2E)-N-{4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}-4-(piperidin-1-yl)but-2-enamide monohydrate
Dacomitinib monohydrate
(2E)-N-(4-(3-Chloro-4-fluorophenyl)amino)7-methoxyquinazolin-6-yl)4-(piperidin-1-yl)but-2-enamide monohydrate
PF-00299804

Chemical & Physical Properties

[ Molecular Formula ]:
C24H27ClFN5O3

[ Molecular Weight ]:
487.95

[ Exact Mass ]:
487.178650

[ PSA ]:
92.10000

[ LogP ]:
5.75120

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds

  • Dacomitinib (PF-00299804)
  • PF-06471553
  • PF-05085727
  • PF-03463275
  • PF-06815189
  • PF-06869206
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide
  • 3-(3,5-Dimethylisoxazol-4-yl)-1-(3-(pyrimidin-2-ylamino)azetidin-1-yl)propan-1-one