Piperazine,1-[(2,3-dihydro-1,4-benzodioxin-2-yl)methyl]-4-phenyl-

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Names

[ CAS No. ]:
1044-59-3

[ Name ]:
Piperazine,1-[(2,3-dihydro-1,4-benzodioxin-2-yl)methyl]-4-phenyl-

[Synonym ]:
McN 261

Chemical & Physical Properties

[ Density]:
1.172g/cm3

[ Boiling Point ]:
449ºC at 760 mmHg

[ Molecular Formula ]:
C19H22N2O2

[ Molecular Weight ]:
310.39000

[ Flash Point ]:
132.1ºC

[ Exact Mass ]:
310.16800

[ PSA ]:
24.94000

[ LogP ]:
2.65150

[ Vapour Pressure ]:
2.97E-08mmHg at 25°C

[ Index of Refraction ]:
1.593

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TL3950000
CHEMICAL NAME :
Piperazine, 1-((2,3-dihydro-1,4-benzodioxin-2-yl)methyl)-4-phenyl -
CAS REGISTRY NUMBER :
1044-59-3
BEILSTEIN REFERENCE NO. :
0318867
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C19-H22-N2-O2
MOLECULAR WEIGHT :
310.43

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YHHPAL Yaoxue Xuebao. Acta Pharmaceutica Sinica. Pharmaceutical Journal. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 1953- Suspended 1966-78. Volume(issue)/page/year: 16,321,1981
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
104 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JACSAT Journal of the American Chemical Society. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1879- Volume(issue)/page/year: 76,5091,1954

Safety Information

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1-Phenylpiperazine
  • 1,4-Benzodioxin,2-(chloromethyl)-2,3-dihydro-

DownStream

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%