Ebselen oxide

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Names

[ CAS No. ]:
104473-83-8

[ Name ]:
Ebselen oxide

[Synonym ]:
2-Phenyl-1,2-benzoselenazol-3(2H)-one 1-oxide
1,2-Benzisoselenazole-1,3-dione, 2-phenyl
1-oxo-2-phenyl-1λ<sup>4</sup>,2-benzoselenazol-3-one
1,2-Benzisoselenazol-3(2H)-one, 2-phenyl-, 1-oxide

Chemical & Physical Properties

[ Boiling Point ]:
277.3±23.0 °C at 760 mmHg

[ Molecular Formula ]:
C13H9NO2Se

[ Molecular Weight ]:
290.176

[ Flash Point ]:
121.5±22.6 °C

[ Exact Mass ]:
290.979858

[ PSA ]:
37.38000

[ LogP ]:
1.53770

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS06, GHS08, GHS09

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301 + H331-H373-H410

[ Precautionary Statements ]:
P261-P273-P301 + P310-P311-P501

[ RIDADR ]:
UN 3283 6.1 / PGII

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • bis(2-(N-phenylcarboxamido)phenyl)diselenide
  • Ebselen
  • Glutathione

DownStream

  • Dibenzyl disulfide
  • Ebselen
  • Heptyl disulfide
  • Dicyclohexyl Disulfide
  • 2-((cyclohexylthio)selanyl)-N-phenylbenzamide
  • bis(2-(N-phenylcarboxamido)phenyl)diselenide
  • 2-vinyl-4H-1,3-dithiin

Articles

AMACR amplification in myxofibrosarcomas: a mechanism of overexpression that promotes cell proliferation with therapeutic relevance.

Clin. Cancer Res. 20(23) , 6141-52, (2014)

Myxofibrosarcomas frequently display arm-level gains on 5p. We characterized the pathogenetic and therapeutic relevance of the α-methylacyl coenzyme A racemase (AMACR) at 5p13.3.AMACR mRNA expression ...

AMACR amplification and overexpression in primary imatinib-naïve gastrointestinal stromal tumors: a driver of cell proliferation indicating adverse prognosis.

Oncotarget 5(22) , 11588-603, (2014)

Non-random gains of chromosome 5p have been observed in clinically aggressive gastrointestinal stromal tumors, whereas the driving oncogenes on 5p remain to be characterized. We used an integrative ge...


More Articles

Related Compounds

  • Ebselen
  • digold oxide
  • Carbon oxide
  • Diphenylphosphine oxide
  • Iron oxide brown
  • Phosphine oxide,[1-(diphenylphosphino)butyl]diphenyl- (9CI)
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  • 1-(1-Bromo-2-methylpropan-2-yl)-2-nitrobenzene
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-(2-Methoxy-2-methylpropoxy)ethane-1-sulfonyl chloride
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 4-(3-amino-2,2-dimethylcyclopropyl)-N,N-diethylaniline
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • 4-Methyl-3-(1,2-thiazol-4-yl)cyclohexan-1-amine
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • 4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-{[(1R)-1-phenylethyl]carbamoyl}butanoic acid