Pramipexole

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Names

[ CAS No. ]:
104632-26-0

[ Name ]:
Pramipexole

[Synonym ]:
N~6~-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine dihydrochloride
n'-propyl-4,5,6,7-tetrahydrobenzothiazole-2,6-diamine
(Pramipexole )
(S)-2-Amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole
(S)-4,5,6,7-Tetrahydro-N6-propyl-2,6-benzothiazolediamine
(S)-N6-Propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine
[(6S)-2-Amino(4,5,6,7-tetrahydrobenzothiazol-6-yl)]propylamine
(S)-Pramipexole
2,6-BENZOTHIAZOLEDIAMINE,4,5,6,7-TETRAHYDRO-N6-PROPYL-, (6S)-
U 98528E
MFCD00869076
(6S)-6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine
Pramipexole
(S)-2-AMINO-6-(PROPYLAMINO)-4,5,6,7-TETRAHYDROBENZOTHIAZOL TETRAHYDROBENZOTHIAZOL
T56 BN DSJ CZ GM3 &&S Form
(s)-2-amino-6-propylamino-4,5,6,7-tetrahydrobenzthiazole
Pramipexole(S)-2-Amino-6-propylamino-4,5,6,7-tetrahydrobenzthiazole
2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N-propyl-, (6S)-
(S)-N6-Propyl-4,5,6,7-tetrahydrobenzothiazole-2,6-diamine
(+)-pramipexole
pramipexol
(6S)-N-Propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
378.0±42.0 °C at 760 mmHg

[ Melting Point ]:
288-290°C

[ Molecular Formula ]:
C10H17N3S

[ Molecular Weight ]:
211.327

[ Flash Point ]:
182.4±27.9 °C

[ Exact Mass ]:
211.114319

[ PSA ]:
79.18000

[ LogP ]:
1.42

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.583

[ Storage condition ]:
-20°C Freezer

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38:Irritating to eyes, respiratory system and skin .

[ Safety Phrases ]:
S26-S36

[ WGK Germany ]:
3

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • rac-cis-7-Hydroxy Pramipexole
  • Propionaldehyde
  • (S)-4,5,6,7-Tetrahydro-2,6-benzothiazolediamine
  • (6S)-2-Amino-6-propionamidotetrahydrobenzothiazole
  • Pramipexole dihydrochloride
  • 1-Bromopropane
  • D-Tartaric acid
  • (±)-Pramipexole
  • 4,5,6,7-TETRAHYDRO-2,6-BENZOTHIAZOLE DIAMINE

DownStream

  • ka-3-7-1
  • 1,2-Benzenediol
  • Pramipexole dihydrochloride

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • PRAMIPEXOLE
  • pramipexole
  • Pramipexole
  • R-Pramipexole
  • Pramipexole-d5
  • Dexpramipexole
  • N-cyclopropyl-6-(3-{[(3-methoxyphenyl)methyl]amino}pyrrolidin-1-yl)pyridine-3-carboxamide
  • N-(3,4-dimethoxyphenyl)-3-(3-ethyl-1,2,4-oxadiazol-5-yl)-7-methyl-1,8-naphthyridin-4-amine
  • Methyl 4-{[3-(3-ethyl-1,2,4-oxadiazol-5-yl)-7-methyl-1,8-naphthyridin-4-yl]amino}benzoate
  • N-(3,4-difluorophenyl)-3-(3-ethyl-1,2,4-oxadiazol-5-yl)-7-methyl-1,8-naphthyridin-4-amine
  • 3-(3-ethyl-1,2,4-oxadiazol-5-yl)-N-(3-fluoro-4-methoxyphenyl)-7-methyl-1,8-naphthyridin-4-amine
  • Methyl 3-({7-methyl-3-[3-(propan-2-yl)-1,2,4-oxadiazol-5-yl]-1,8-naphthyridin-4-yl}amino)benzoate
  • 3-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)-N-(3,4-difluorophenyl)-7-methyl-1,8-naphthyridin-4-amine
  • 1-[3-(3-isopropyl-1,2,4-oxadiazol-5-yl)-2-pyridyl]-N~4~-(4-methoxyphenyl)-1H-imidazole-4-carboxamide
  • 1-[4-(3-tert-butyl-1,2,4-oxadiazol-5-yl)pyridin-2-yl]-N-(4-chlorobenzyl)-1H-imidazole-4-carboxamide
  • N~4~-(3-chlorobenzyl)-1-[4-(3-isopropyl-1,2,4-oxadiazol-5-yl)-2-pyridyl]-1H-imidazole-4-carboxamide