Dexpramipexole

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Names

[ CAS No. ]:
104632-28-2

[ Name ]:
Dexpramipexole

[Synonym ]:
Dexpramipexole
(6R)-2-amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole
(R)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine
(6R)-4,5,6,7-tetrahydro-N6-propylbenzothiazole-2,6-diamine
(R)-Pramipexole Dihydrochloride
Pramipexole [USAN:INN]
(R)-(+)-2-amino-4,5,6,7-tetrahydro-6-(n-propylamino)benzothiazole
(R)-Pramipexole
(R)-(+)-pramipexole

Chemical & Physical Properties

[ Density]:
1.17±0.1 g/cm3

[ Melting Point ]:
270-272ºC

[ Molecular Formula ]:
C10H17N3S

[ Molecular Weight ]:
211.331

[ PSA ]:
83.52000

[ LogP ]:
4.38490

[ Water Solubility ]:
Slightly soluble (1.1 g/L) (25 ºC)

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (R)-N-(2-AMINO-4,5,6,7-TETRAHYDROBENZO[D]THIAZOL-6-YL)PROPIONAMIDE
  • D-Tartaric acid
  • (±)-Pramipexole
  • (+)-(6R)-2,6-diamino-4,5,6,7-tetrahydrobenzothiazole
  • 4,5,6,7-TETRAHYDRO-2,6-BENZOTHIAZOLE DIAMINE

DownStream

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • DEXPRAMIPEXOLE DIHYDROCHLORIDE
  • Dexpramipexole (dihydrochloride)
  • Dexpramipexole-d3 dihydrochloride
  • Dexpramipexole dihydrochloride anhydrous
  • 5-fluoro-3-methyl-N-(5-methyl-4,5,6,7-tetrahydro-2,1-benzisoxazol-3-yl)-1-benzofuran-2-carboxamide
  • {[2-(Morpholin-4-yl)-5-(trifluoromethyl)phenyl]carbamoyl}methyl 3,6-dichloropyridine-2-carboxylate
  • N-[4-(1H-tetrazol-1-yl)phenyl]pentanamide
  • [(2,3-Dichlorophenyl)methyl](propyl)amine hydrochloride
  • 2-(4-chlorophenyl)-N-[4-(1H-tetrazol-1-yl)phenyl]acetamide
  • 5-(2,3-dihydro-1,4-benzodioxin-6-yl)-N-{4-[(E)-phenyldiazenyl]phenyl}-1,2-oxazole-3-carboxamide
  • 6-allyl-4-(4-(benzyloxy)phenyl)-3,4,6,7-tetrahydro-1H-pyrrolo[3,4-d]pyrimidine-2,5-dione
  • 13-Ethyl-8-(2-methylphenyl)-5-oxa-2,11,13-triazatricyclo[7.4.0.0^{3,7}]trideca-1(9),3(7)-diene-6,10,12-trione
  • 4-methyl-4H,5H,6H,7H-thieno[3,2-c]pyridine hydrochloride
  • 4-(4-(benzyloxy)phenyl)-6-propyl-3,4,6,7-tetrahydro-1H-pyrrolo[3,4-d]pyrimidine-2,5-dione
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