Dexpramipexole

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Names

[ Name ]:
Dexpramipexole

[Synonym ]:
Dexpramipexole
(6R)-2-amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole
(R)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine
(6R)-4,5,6,7-tetrahydro-N6-propylbenzothiazole-2,6-diamine
(R)-Pramipexole Dihydrochloride
Pramipexole [USAN:INN]
(R)-(+)-2-amino-4,5,6,7-tetrahydro-6-(n-propylamino)benzothiazole
(R)-Pramipexole
(R)-(+)-pramipexole

Chemical & Physical Properties

[ Density]:
1.17±0.1 g/cm3

[ Melting Point ]:
270-272ºC

[ Molecular Formula ]:
C₁₀H₁₇N₃S

[ Molecular Weight ]:
211.331

[ PSA ]:
83.52000

[ LogP ]:
4.38490

[ Water Solubility ]:
Slightly soluble (1.1 g/L) (25 ºC)

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

(R)-N-(2-AMINO-4,5,6,7-TETRAHYDROBENZO[D]THIAZOL-6-YL)PROPIONAMIDE
D-Tartaric acid
(±)-Pramipexole
(+)-(6R)-2,6-diamino-4,5,6,7-tetrahydrobenzothiazole
4,5,6,7-TETRAHYDRO-2,6-BENZOTHIAZOLE DIAMINE

DownStream

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

DEXPRAMIPEXOLE DIHYDROCHLORIDE
Dexpramipexole (dihydrochloride)
Dexpramipexole-d3 dihydrochloride
Dexpramipexole dihydrochloride anhydrous
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1-(4-Methoxybenzyl)piperidine-4-carbaldehyde
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
(4-Methyl-tetrahydro-furan-2-yl)-methanol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
tert-Butyl-DL-alanine
4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide