Phenylacetic acid mustard
Suppliers
Names
[ CAS No. ]:
10477-72-2
[ Name ]:
Phenylacetic acid mustard
[Synonym ]:
PAAM
Chlorphenacyl
Phenylacetic acid mustard
Khlorfenatsil
Chlorphenacil
Phenacid
Phenylacetic mustard
Chemical & Physical Properties
[ Boiling Point ]:
195.5ºC at 760 mmHg
[ Molecular Formula ]:
C12H15Cl2NO2
[ Molecular Weight ]:
276.15900
[ Flash Point ]:
89.6ºC
[ Exact Mass ]:
275.04800
[ PSA ]:
40.54000
[ LogP ]:
2.59770
[ Vapour Pressure ]:
0.418mmHg at 25°C
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AF5456000
- CHEMICAL NAME :
- Acetic acid, 2-(p-(bis(2-chloroethyl)amino)phenyl)-
- CAS REGISTRY NUMBER :
- 10477-72-2
- BEILSTEIN REFERENCE NO. :
- 0960062
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 11
- MOLECULAR FORMULA :
- C12-H15-Cl2-N-O2
- MOLECULAR WEIGHT :
- 276.18
- WISWESSER LINE NOTATION :
- QV1R DN2G2G
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 15 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 15900 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 10 mg/kg
- SEX/DURATION :
- female 14 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - ovaries, fallopian tubes Reproductive - Maternal Effects - ovaries, fallopian tubes
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 8 mg/kg
- SEX/DURATION :
- male 14 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland, accessory glands
- TYPE OF TEST :
- Sex chromosome loss and nondisjunction
- TYPE OF TEST :
- Sex chromosome loss and nondisjunction
MUTATION DATA
- TYPE OF TEST :
- DNA damage
- TEST SYSTEM :
- Rodent - hamster Fibroblast
- DOSE/DURATION :
- 1500 umol/L
- REFERENCE :
- BEXBAN Bulletin of Experimental Biology and Medicine (English Translation). Translation of BEBMAE. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) V.41- 1956- Volume(issue)/page/year: 92,943,1981
Safety Information
[ HS Code ]:
2922499990
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2922499990
[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%