Ecabapide

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Names

[ CAS No. ]:
104775-36-2

[ Name ]:
Ecabapide

[Synonym ]:
Benzamide,3-((2-((2-(3,4-dimethoxyphenyl)ethyl)amino)-2-oxoethyl)amino)-N-methyl
Ecabapide
m-((((3,4-Dimethoxyphenethyl)carbamoyl)methyl)amino)-N-methylbenzamide
3-((2-((2-(3,4-Dimethoxyphenyl)ethyl)amino)-2-oxoethyl)amino)-N-methylbenzamide
DQ2511
Ecabamide
Muralis

Chemical & Physical Properties

[ Density]:
1.185g/cm3

[ Boiling Point ]:
658.6ºC at 760mmHg

[ Molecular Formula ]:
C20H25N3O4

[ Molecular Weight ]:
371.43000

[ Flash Point ]:
352.1ºC

[ Exact Mass ]:
371.18500

[ PSA ]:
88.69000

[ LogP ]:
2.68900

[ Vapour Pressure ]:
3.23E-17mmHg at 25°C

[ Index of Refraction ]:
1.583

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CV4375600
CHEMICAL NAME :
Benzamide, 3-((2-((2-(3,4-dimethoxyphenyl)ethyl)amino)-2-oxoethy l)amino)-N-methyl-
CAS REGISTRY NUMBER :
104775-36-2
LAST UPDATED :
199706
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C20-H25-N3-O4
MOLECULAR WEIGHT :
371.48

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
16800 mg/kg/4W-I
TOXIC EFFECTS :
Blood - normocytic anemia Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - dehydrogenases Biochemical - Effect on specific coenzyme - not otherwise specified
REFERENCE :
FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 20,141,1993
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
4200 mg/kg/7D-I
TOXIC EFFECTS :
Liver - other changes Blood - other changes
REFERENCE :
FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 32,269,1996

Related Compounds

  • (2R)-2-{[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-methyl-1,3-thiazol-5-yl]formamido}-3-hydroxypropanoic acid
  • 2-{2-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methoxybutanamido]ethoxy}acetic acid
  • 2-({1-[(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanoyl]-3-methylazetidin-3-yl}oxy)acetic acid
  • 4-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)pent-4-ynamido]-3-methoxybutanoic acid
  • 4-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methoxybutanamido]-3-methylbutanoic acid
  • 3-{[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2,6-difluorophenyl]formamido}-2-methylpropanoic acid
  • 3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-{7-methyl-2,7-diazaspiro[4.4]nonan-2-yl}-4-oxobutanoic acid
  • (2S)-3-{[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2,6-difluorophenyl]formamido}-2-hydroxypropanoic acid
  • 3-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-methoxy-N-methylbutanamido]oxolane-3-carboxylic acid
  • 3-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-N,5,5-trimethylhexanamido]-2-methylpropanoic acid
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