7-Methylguanosine 5'-diphosphate sodium

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Names

[ CAS No. ]:
104809-16-7

[ Name ]:
7-Methylguanosine 5'-diphosphate sodium

[Synonym ]:
MFCD00057869

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₁H₁₉N₅O₁₁P₂

[ Molecular Weight ]:
459.24300

[ Exact Mass ]:
459.05600

[ PSA ]:
260.85000

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Elimination of cap structures generated by mRNA decay involves the new scavenger mRNA decapping enzyme Aph1/FHIT together with DcpS.

Nucleic Acids Res. 43(1) , 482-92, (2015)

Eukaryotic 5' mRNA cap structures participate to the post-transcriptional control of gene expression before being released by the two main mRNA decay pathways. In the 3'-5' pathway, the exosome genera...

Loss of the scavenger mRNA decapping enzyme DCPS causes syndromic intellectual disability with neuromuscular defects.

Hum. Mol. Genet. 24(11) , 3163-71, (2015)

mRNA decay is an essential and active process that allows cells to continuously adapt gene expression to internal and environmental cues. There are two mRNA degradation pathways: 3' to 5' and 5' to 3'...

7-methylguanosine diphosphate (m(7)GDP) is not hydrolyzed but strongly bound by decapping scavenger (DcpS) enzymes and potently inhibits their activity.

Biochemistry 51(40) , 8003-13, (2012)

Decapping scavenger (DcpS) enzymes catalyze the cleavage of a residual cap structure following 3' → 5' mRNA decay. Some previous studies suggested that both m(7)GpppG and m(7)GDP were substrates for D...

2',3'-O-(1-(2-carboxyethyl)ethylidene)-7-methylguanosine 5'-diphosphate
7-METHYLGUANOSINE 5'-TRIPHOSPHATE SODIUM SALT
7-methylguanosine 5'-monophosphate*sodiu m
7-methylguanosine-5'-triphosphoryl-2'-O-methylguanosine
7-methylguanosine-5'-monophosphate
8-Azidoadenosine-5'-diphosphate Sodium Salt