7-Methylguanosine 5'-diphosphate sodium

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Names

[ CAS No. ]:
104809-16-7

[ Name ]:
7-Methylguanosine 5'-diphosphate sodium

[Synonym ]:
MFCD00057869

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₁H₁₉N₅O₁₁P₂

[ Molecular Weight ]:
459.24300

[ Exact Mass ]:
459.05600

[ PSA ]:
260.85000

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Elimination of cap structures generated by mRNA decay involves the new scavenger mRNA decapping enzyme Aph1/FHIT together with DcpS.

Nucleic Acids Res. 43(1) , 482-92, (2015)

Eukaryotic 5' mRNA cap structures participate to the post-transcriptional control of gene expression before being released by the two main mRNA decay pathways. In the 3'-5' pathway, the exosome genera...

Loss of the scavenger mRNA decapping enzyme DCPS causes syndromic intellectual disability with neuromuscular defects.

Hum. Mol. Genet. 24(11) , 3163-71, (2015)

mRNA decay is an essential and active process that allows cells to continuously adapt gene expression to internal and environmental cues. There are two mRNA degradation pathways: 3' to 5' and 5' to 3'...

7-methylguanosine diphosphate (m(7)GDP) is not hydrolyzed but strongly bound by decapping scavenger (DcpS) enzymes and potently inhibits their activity.

Biochemistry 51(40) , 8003-13, (2012)

Decapping scavenger (DcpS) enzymes catalyze the cleavage of a residual cap structure following 3' → 5' mRNA decay. Some previous studies suggested that both m(7)GpppG and m(7)GDP were substrates for D...

2',3'-O-(1-(2-carboxyethyl)ethylidene)-7-methylguanosine 5'-diphosphate
7-METHYLGUANOSINE 5'-TRIPHOSPHATE SODIUM SALT
7-methylguanosine 5'-monophosphate*sodiu m
7-methylguanosine-5'-triphosphoryl-2'-O-methylguanosine
7-methylguanosine-5'-monophosphate
8-Azidoadenosine-5'-diphosphate Sodium Salt
1-(1-Pivaloylindolin-6-yl)-3-((tetrahydrofuran-2-yl)methyl)urea
N'-(4-amino-6-methylpyrimidin-2-yl)pivalohydrazide hydrochloride
N'-(4-amino-6-methylpyrimidin-2-yl)furan-2-carbohydrazide hydrochloride
N2-(4-chlorophenethyl)-6-methylpyrimidine-2,4-diamine hydrochloride
N2-(2-(1H-indol-3-yl)ethyl)-6-methylpyrimidine-2,4-diamine hydrochloride
N-{[1-(oxan-4-yl)piperidin-4-yl]methyl}adamantane-1-carboxamide
2-(3-methoxyphenyl)-N-((1-(tetrahydrothiophen-3-yl)piperidin-4-yl)methyl)acetamide
N-(2-(4-(3-(thiophen-3-yl)-1,2,4-oxadiazol-5-yl)-1H-1,2,3-triazol-1-yl)ethyl)pyrazine-2-carboxamide
N-(3-fluoro-2-methylphenyl)-5-(3-(thiophen-3-yl)-1,2,4-oxadiazol-5-yl)pyrimidin-4-amine
1-(2-Chlorophenyl)-3-(2-(pyrimidin-5-yl)ethyl)urea

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