7-Methylguanosine 5'-diphosphate sodium

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Names

[ CAS No. ]:
104809-16-7

[ Name ]:
7-Methylguanosine 5'-diphosphate sodium

[Synonym ]:
MFCD00057869

Chemical & Physical Properties

[ Molecular Formula ]:
C11H19N5O11P2

[ Molecular Weight ]:
459.24300

[ Exact Mass ]:
459.05600

[ PSA ]:
260.85000

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Elimination of cap structures generated by mRNA decay involves the new scavenger mRNA decapping enzyme Aph1/FHIT together with DcpS.

Nucleic Acids Res. 43(1) , 482-92, (2015)

Eukaryotic 5' mRNA cap structures participate to the post-transcriptional control of gene expression before being released by the two main mRNA decay pathways. In the 3'-5' pathway, the exosome genera...

Loss of the scavenger mRNA decapping enzyme DCPS causes syndromic intellectual disability with neuromuscular defects.

Hum. Mol. Genet. 24(11) , 3163-71, (2015)

mRNA decay is an essential and active process that allows cells to continuously adapt gene expression to internal and environmental cues. There are two mRNA degradation pathways: 3' to 5' and 5' to 3'...

7-methylguanosine diphosphate (m(7)GDP) is not hydrolyzed but strongly bound by decapping scavenger (DcpS) enzymes and potently inhibits their activity.

Biochemistry 51(40) , 8003-13, (2012)

Decapping scavenger (DcpS) enzymes catalyze the cleavage of a residual cap structure following 3' → 5' mRNA decay. Some previous studies suggested that both m(7)GpppG and m(7)GDP were substrates for D...


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Related Compounds

  • 2',3'-O-(1-(2-carboxyethyl)ethylidene)-7-methylguanosine 5'-diphosphate
  • 7-METHYLGUANOSINE 5'-TRIPHOSPHATE SODIUM SALT
  • 7-methylguanosine 5'-monophosphate*sodiu m
  • 7-methylguanosine-5'-triphosphoryl-2'-O-methylguanosine
  • 7-methylguanosine-5'-monophosphate
  • 8-Azidoadenosine-5'-diphosphate Sodium Salt
  • 2-[(1R,2S,4R)-2-Amino-4-[(2-methylpropan-2-yl)oxy]cyclobutyl]acetic acid;hydrochloride
  • 6-Cyclopropyl-N-(3,4,5-trimethoxyphenyl)pyrimidine-4-carboxamide
  • 2-Ethoxy-4-formylbenzoic acid
  • 4-Prop-2-enylpiperidine-4-carboxylic acid;hydrochloride
  • 2-Methyl-3,4,10,10a-tetrahydro-1H-chromeno[3,2-c]pyridine-4a,10-diol
  • 5-Iodo-6-methyl-1,7-naphthyridine
  • 5-Chloro-6-(4,4-difluoropiperidin-1-yl)pyridine-3-carbonitrile
  • 3,5-Dimethyl-1-{[4-(trifluoromethyl)phenyl]methanesulfonyl}piperidine
  • 2-{1-[(5-methyl-1,2-oxazol-4-yl)methyl]azetidin-3-yl}-2H-1,2,3-triazole
  • 5-chloro-2-({1-[(4,5-dimethyl-4H-1,2,4-triazol-3-yl)methyl]piperidin-4-yl}oxy)pyrimidine
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