NAAD sodium salt

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Names

[ CAS No. ]:
104809-30-5

[ Name ]:
NAAD sodium salt

[Synonym ]:
Nicotinic acid NAD
Deamido NAD
Nicotinic acid adenine dinucleotide sodium salt
NAAD

Chemical & Physical Properties

[ Molecular Formula ]:
C21H25N6NaO15P2

[ Molecular Weight ]:
686.39

[ Exact Mass ]:
686.07500

[ PSA ]:
337.75000

[ Storage condition ]:
20°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

Articles

Mechanism of sirtuin inhibition by nicotinamide: altering the NAD(+) cosubstrate specificity of a Sir2 enzyme.

Mol. Cell. 17 , 855-868, (2005)

Sir2 enzymes form a unique class of NAD(+)-dependent deacetylases required for diverse biological processes, including transcriptional silencing, regulation of apoptosis, fat mobilization, and lifespa...

Crystal structures of E. coli nicotinate mononucleotide adenylyltransferase and its complex with deamido-NAD.

Structure 10 , 69-79, (2002)

Nicotinamide/Nicotinate mononucleotide (NMN/NaMN) adenylyltransferase is an indispensable enzyme in both de novo biosynthesis and salvage of NAD+ and NADP+. In prokaryotes, it is absolutely required f...

Sir2 regulation by nicotinamide results from switching between base exchange and deacetylation chemistry.

Biochemistry 42 , 9249-9256, (2003)

Life span regulation and inhibition of gene silencing in yeast have been linked to nicotinamide effects on Sir2 enzymes. The Sir2 enzymes are NAD(+)-dependent protein deacetylases that influence gene ...


More Articles

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