ethyl 2-bromoacetate

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Names

[ CAS No. ]:
105-36-2

[ Name ]:
ethyl 2-bromoacetate

[Synonym ]:
ETHYL BROMOACETATE/BROMOACETIC ACID ETHYL ESTER
4-Methoxybenzyl alcohol
Bromoacetic Acid Ethyl Ester
BROMOACETICACIDETHYLESTER
2-BROMOACETIC ACID ETHYL ESTER
Ethylbromoacetate
BROMO ACETIC ACID ETHYL ESTER
Ethyl Bromoacetate
MFCD00000191
EINECS 203-290-9
ethyl 2-bromoacetate
ETHYL BROMOACETATE FOR SYNTHESIS
Ethyl2-Bromoacetate

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
168.5±0.0 °C at 760 mmHg

[ Melting Point ]:
-38 °C

[ Molecular Formula ]:
C₄H₇BrO₂

[ Molecular Weight ]:
167.001

[ Flash Point ]:
47.8±0.0 °C

[ Exact Mass ]:
165.962936

[ PSA ]:
26.30000

[ LogP ]:
1.37

[ Vapour Pressure ]:
1.6±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.453

[ Stability ]:
Stable. Combustible. Incompatible with strong oxidizing agents, water, strong acids.

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AF6000000

CHEMICAL NAME :: Acetic acid, bromo-, ethyl ester

CAS REGISTRY NUMBER :: 105-36-2

BEILSTEIN REFERENCE NO. :: 0506456

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C4-H7-Br-O2

MOLECULAR WEIGHT :: 167.02

WISWESSER LINE NOTATION :: E1VO2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 252 mg/kg/63W-I

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Tumorigenic - tumors at site of application

REFERENCE :: JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8. Volume(issue)/page/year: 53,695,1974 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4664 No. of Facilities: 17 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 851 (estimated) No. of Female Employees: 187 (estimated)

Safety Information

[ Symbol ]:

GHS02, GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H226-H300 + H310 + H330

[ Precautionary Statements ]:
Missing Phrase - N15.00950417-P210-P280-P302 + P352 + P310-P304 + P340 + P310-P370 + P378

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
T+:Verytoxic;

[ Risk Phrases ]:
R26/27/28

[ Safety Phrases ]:
S26-S45-S7/9-S1/2

[ RIDADR ]:
UN 1603 6.1/PG 2

[ WGK Germany ]:
1

[ RTECS ]:
AF6000000

[ Packaging Group ]:
II

[ Hazard Class ]:
6.1

[ HS Code ]:
29159080

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

EDA
Ethanol
Bromoacetic acid
Ethoxyethene
tris(dimethylamino)((2-ethoxy-2-oxoethyl)thio)phosphonium
acetic acid
Ethanoic anhydride
Tert-Butylthiol
Bromoacetyl chloride
Bromoacetyl bromide

DownStream

Ethyl 3-(4-(trifluoromethyl)phenyl)acrylate
ethyl 2-(3-methyl-1,2-dihydroimidazol-1-ium-1-yl)acetate,bromide
ethyl 2-(cyanomethoxy)acetate
ETHYL 3-(2-ETHOXY-2-OXOETHOXY)PICOLINATE
Tetraethyl(ethoxycarbonylethylidene)bisphosphonate
Ethyl 3-cyano-3-(6-methoxy-3-nitro-2-pyridinyl)propanoate
ethyl 2-(3-formyl-4-nitrophenoxy)acetate
(2-HYDROXYETHYL)TRIETHYLAMMONIUMIODIDE
1-ethoxyethenyl 2,2-dimethylpropanoate
ETHYL 3-(O-TOLYL)PROPANOATE

Customs

[ HS Code ]: 2915900090

[ Summary ]:
2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%

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ethyl 2-bromoacetate
2-butoxyethoxyethyl 2-bromoacetate
2-ethoxyethoxyethyl 2-bromoacetate
2-methoxyethoxyethyl 2-bromoacetate
2-trimethylsilylethyl 2-bromoacetate
2-(4-tert-butylphenoxy)ethyl 2-bromoacetate
2-(4-Bromophenyl)-1-(methylsulfonyl)pyrrolidine
Tert-butyl 4-(dimethylsulfamoyl)-1,4-diazepane-1-carboxylate
N-(3-bromo-5-fluorobenzyl)methanesulfonamide
N-(3-chlorophenyl)-2-((1-(furan-2-ylmethyl)-5-phenyl-1H-imidazol-2-yl)thio)acetamide
N-Neopentyl-1''H-phenothiazine-1''-carboxamide
N-(4-chlorophenyl)-2-({1-[(furan-2-yl)methyl]-5-phenyl-1H-imidazol-2-yl}sulfanyl)acetamide
2-((1-(furan-2-ylmethyl)-5-(4-methoxyphenyl)-1H-imidazol-2-yl)thio)-1-(pyrrolidin-1-yl)ethanone
2-((1-(furan-2-ylmethyl)-5-(4-methoxyphenyl)-1H-imidazol-2-yl)thio)-N-(p-tolyl)acetamide
N-{3-[methyl(phenyl)amino]propyl}-10H-phenothiazine-10-carboxamide
N-(3-chlorophenyl)-2-((1-(furan-2-ylmethyl)-5-(4-methoxyphenyl)-1H-imidazol-2-yl)thio)acetamide

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