Ethyl 3-oxoglutarate

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Names

[ CAS No. ]:
105-50-0

[ Name ]:
Ethyl 3-oxoglutarate

[Synonym ]:
Diethyl acetone-1,3-dicarboxylate or 3-Oxo-pentanedioic acid, diethy ester
ETHYL ACETONEDICARBOXYLATE
Glutaric acid, 3-oxo-, diethyl ester
Ethyl 3-oxoglutarate
diethylacetone dicarboxylate
Pentanedioic acid, 3-oxo-, diethyl ester
DIETHYL 3-KETOGLUTARATE
DIETHYL 3-OXOGLUTARATE
Diethyl-3-oxopentaediote
Diethyl β-oxoglutarate
1,3-Acetonedicarboxylic Acid Diethyl Ester
3-Oxopentanedioic acid diethyl ester
Diethyl 3-oxopentanedioate
Glutaric acid, 3-oxo-, diethyl ester (8CI)
EINECS 203-302-2
3-oxoglutaric acid diethyl ester
Diethyl-3-oxo-pentan
Diethyl Acetone-1,3-Dicarboxylate
MFCD00009200

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
250.0±0.0 °C at 760 mmHg

[ Molecular Formula ]:
C9H14O5

[ Molecular Weight ]:
202.21

[ Flash Point ]:
86.1±0.0 °C

[ Exact Mass ]:
202.084122

[ PSA ]:
69.67000

[ LogP ]:
2.08

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.435

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
10 g/L (20 ºC)

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
F: Flammable;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S23-S24/25

[ RIDADR ]:
UN 2810

[ WGK Germany ]:
3

[ HS Code ]:
2942000000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Citric Acid
  • Ethanol
  • 3-Oxopentanedioic acid
  • ketene
  • malonoyl chloride
  • 3-carboxymethyl-3-hydroxy-glutaric acid
  • Diethyloxalate
  • Acetone
  • ethyl 3-amino-3-(2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-ylidene)propanoate
  • 1,1,5,5-tetrachloropenta-1,4-dien-3-one

DownStream

  • 4,6-Dichloronicotinoyl chloride
  • Diethyl 3-hydroxypentanedioate
  • 5-heptylresorcinol
  • Ethyl 4,6-dichloronicotinate
  • Oxalic acid
  • Hydroxypropionic acid
  • 3-hydroxyglutamic acid
  • Benzofuroxan

Customs

[ HS Code ]: 2918300090

[ Summary ]:
2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

Synthesis and antitumor cytotoxicity evaluation of pyrido[4,3,2-de]quinolines and isoquinolino[6,5,4,3-cde]quinolines.

Anticancer Drug Des. 15(2) , 99-108, (2000)

A series of novel pyrido[4,3,2-de]quinoline and isoquinolino[6,5,4,3-cde] quinoline compounds was synthesized and evaluated for cytotoxicity in the National Cancer Institute developmental therapeutics...

A synthesis of the pyrazomycins.

J. Org. Chem. 41(2) , 287-90, (1976)

A practical synthesis of (±)-thienamycin. Melillo DG, et al.

Tetrahedron Lett. 21(29) , 2783-86, (1980)


More Articles

Related Compounds

  • Ethyl 2-[(E,E)-2,4-hexadienyl]-3-oxoglutarate
  • ethyl 3-[(2,4-dinitrophenyl)disulfanyl]propanoate
  • ethyl 3-(N-hydroxy-C-methylcarbonimidoyl)-6-methylhept-5-enoate
  • ethyl 3-ethyl-2-(3-phenoxypropanoylimino)benzothiazole-6-carboxylate
  • ethyl 3-(benzylamino)-3-phenylprop-2-enoate
  • ethyl 3-(3-nitrophenyl)-4-oxopent-2-enoate