Dolutegravir (GSK1349572)
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Names
[ CAS No. ]:
1051375-16-6
[ Name ]:
Dolutegravir (GSK1349572)
[Synonym ]:
2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(2,4-difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)-
(4R,12aS)-N-(2,4-Difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
(4R,12aS)-N-[(2,4-difluorophenyl)methyl]-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
GSK 1349572
S-349572
Tivicay
(4R,12aS)-N-[(2,4-difluorophenyl)methyl]-7-hydroxy-4-methyl-6,8-dioxo-3,4,12,12a-tetrahydro-2H-pyrido[5,6]pyrazino[2,6-b][1,3]oxazine-9-carboxamide
Dolutegravir
GSK1349572
Chemical & Physical Properties
[ Density]:
1.53 g/cm3
[ Boiling Point ]:
669.0±55.0 °C at 760 mmHg
[ Molecular Formula ]:
C20H19F2N3O5
[ Molecular Weight ]:
419.379
[ Flash Point ]:
358.4±31.5 °C
[ Exact Mass ]:
419.129272
[ PSA ]:
104.36000
[ LogP ]:
-1.32
[ Vapour Pressure ]:
0.0±2.1 mmHg at 25°C
[ Index of Refraction ]:
1.650
Safety Information
[ Hazard Codes ]:
Xi