4-amino-1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-methyloxolan-2-yl]-5-iodopyrimidin-2-one

Names

[ CAS No. ]:
105309-31-7

[ Name ]:
4-amino-1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-methyloxolan-2-yl]-5-iodopyrimidin-2-one

[Synonym ]:
5'-deoxy-FIAC

Chemical & Physical Properties

[ Density]:
2.31g/cm3

[ Boiling Point ]:
457.4ºC at 760 mmHg

[ Molecular Formula ]:
C9H11FIN3O3

[ Molecular Weight ]:
355.10500

[ Flash Point ]:
230.4ºC

[ Exact Mass ]:
354.98300

[ PSA ]:
91.36000

[ LogP ]:
0.38880

[ Vapour Pressure ]:
2.75E-10mmHg at 25°C

[ Index of Refraction ]:
1.761

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-amino-1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-methyloxolan-2-yl]pyrimidin-2-one
  • 1-(2,5-dideoxy-2-fluoro-5-iodo-β-D-arabinofuranosyl)-5-iodocytosine
  • Fiacitabine

DownStream

Related Compounds

  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • ((1R,5R,7S)-4-Oxa-1-azabicyclo[3.2.1]octan-7-YL)methanol
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • rac-[(1R,2R)-2-(3-chloro-2,4-difluorophenyl)cyclopropyl]methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • 2-{2,2-Dimethyl-1-[(prop-2-en-1-yloxy)carbonyl]pyrrolidin-3-yl}-2-fluoroacetic acid
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • 4-Chloro-3-(chloromethyl)benzene-1-sulfonyl fluoride
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide