(3S,4S)-1-(tert-butoxycarbonylmethyl)-3-[(1R)-1-tert-butyldimethylsilyloxyethyl]-4-[(1R)-1-phenylthiocarbonylethyl]-2-azetidinone

Names

[ CAS No. ]:
105318-06-7

[ Name ]:
(3S,4S)-1-(tert-butoxycarbonylmethyl)-3-[(1R)-1-tert-butyldimethylsilyloxyethyl]-4-[(1R)-1-phenylthiocarbonylethyl]-2-azetidinone

Chemical & Physical Properties

[ Molecular Formula ]:
C26H41NO5SSi

[ Molecular Weight ]:
507.75800

[ Exact Mass ]:
507.24700

[ PSA ]:
98.21000

[ LogP ]:
5.45830

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (2R)-2-[(2S,3S)-3-{(1R)-1-(t-butyldimethylsilyloxy)ethyl}-4-oxoazetidin-2-yl]propionic acid
  • (3S,4S)-1-(tert-butoxycarbonylmethyl)-3-[(1R)-1-tert-butyldimethylsilyloxyethyl]-4-[(1R)-1-carboxyethyl]-2-azetidinone

DownStream

  • Protected meropenem
  • (3S,4S)-1-(p-nitrobenzyloxycarbonylmethyl)-4-[(1R)-1-phenylthiocarbonylethyl]-3-[(1R)-1-trimethylsilyloxyethyl]-2-azetidinone

Related Compounds

  • 2-acetamido-3-(1-methyl-1H-pyrazol-5-yl)propanoic acid
  • 4-(1-Methyl-1H-pyrazol-5-yl)pyrrolidine-3-carboxylic acid
  • Methyl 4-(1-methyl-1H-pyrazol-5-yl)pyrrolidine-3-carboxylate
  • ethyl 4-(1-methyl-1H-pyrazol-5-yl)pyrrolidine-3-carboxylate
  • 1-ethyl-2-(1-methyl-1H-pyrazol-5-yl)-6-oxopiperidine-3-carboxylic acid
  • [1-methyl-2-(1-methyl-1H-pyrazol-5-yl)piperidin-3-yl]methanamine
  • [4-methyl-3-(1-methyl-1H-pyrazol-5-yl)morpholin-2-yl]methanamine
  • Methyl({[1-methyl-2-(1-methyl-1H-pyrazol-5-yl)piperidin-3-yl]methyl})amine
  • [1-cyclopropyl-2-(1-methyl-1H-pyrazol-5-yl)piperidin-3-yl]methanamine
  • [4-ethyl-3-(1-methyl-1H-pyrazol-5-yl)morpholin-2-yl]methanamine
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