(3S,4S)-1-(tert-butoxycarbonylmethyl)-3-[(1R)-1-tert-butyldimethylsilyloxyethyl]-4-[(1R)-1-phenylthiocarbonylethyl]-2-azetidinone

Names

[ CAS No. ]:
105318-06-7

[ Name ]:
(3S,4S)-1-(tert-butoxycarbonylmethyl)-3-[(1R)-1-tert-butyldimethylsilyloxyethyl]-4-[(1R)-1-phenylthiocarbonylethyl]-2-azetidinone

Chemical & Physical Properties

[ Molecular Formula ]:
C26H41NO5SSi

[ Molecular Weight ]:
507.75800

[ Exact Mass ]:
507.24700

[ PSA ]:
98.21000

[ LogP ]:
5.45830

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (2R)-2-[(2S,3S)-3-{(1R)-1-(t-butyldimethylsilyloxy)ethyl}-4-oxoazetidin-2-yl]propionic acid
  • (3S,4S)-1-(tert-butoxycarbonylmethyl)-3-[(1R)-1-tert-butyldimethylsilyloxyethyl]-4-[(1R)-1-carboxyethyl]-2-azetidinone

DownStream

  • Protected meropenem
  • (3S,4S)-1-(p-nitrobenzyloxycarbonylmethyl)-4-[(1R)-1-phenylthiocarbonylethyl]-3-[(1R)-1-trimethylsilyloxyethyl]-2-azetidinone

Related Compounds

  • 1-cyclopentyl-N-(2-methoxybenzyl)-6-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxamide
  • N-benzyl-2-(5-methyl-1H-tetrazol-1-yl)benzamide
  • 2-(cyclopropylamino)-N-[2-(4-sulfamoylphenyl)ethyl]-1,3-thiazole-4-carboxamide
  • 2-(3-(4-benzylpiperidin-1-yl)-6-oxopyridazin-1(6H)-yl)-N-(3-methoxyphenyl)acetamide
  • 2-benzyl-N-[5-(methoxymethyl)-1,3,4-thiadiazol-2-yl]-1-oxo-1,2-dihydroisoquinoline-4-carboxamide
  • N-cyclooctyl-4-(6-methoxy[1,2,4]triazolo[4,3-b]pyridazin-3-yl)butanamide
  • 4-(4-chlorophenyl)-N-{2-oxo-2-[(pyridin-4-ylmethyl)amino]ethyl}piperazine-1-carboxamide
  • [4-(3-methoxyphenyl)piperazin-1-yl][2-(5-methyl-1H-tetrazol-1-yl)phenyl]methanone
  • N-(1,3-benzothiazol-2-yl)-3-(6-methoxy[1,2,4]triazolo[4,3-b]pyridazin-3-yl)propanamide
  • N-(heptan-2-yl)-3-(5-methyl-1H-tetrazol-1-yl)benzamide
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