(3S,4S)-1-(p-nitrobenzyloxycarbonylmethyl)-4-[(1R)-1-phenylthiocarbonylethyl]-3-[(1R)-1-trimethylsilyloxyethyl]-2-azetidinone

Names

[ CAS No. ]:
105318-32-9

[ Name ]:
(3S,4S)-1-(p-nitrobenzyloxycarbonylmethyl)-4-[(1R)-1-phenylthiocarbonylethyl]-3-[(1R)-1-trimethylsilyloxyethyl]-2-azetidinone

[Synonym ]:
(3S,4S)-3-[(1R)-1-trimethylsilyloxyethyl]-4-[(1R)-1-phenylthiocarbonylethyl]-1-(p-nitrobenzyloxycarbonylmethyl]azetidin-2-one

Chemical & Physical Properties

[ Molecular Formula ]:
C26H32N2O7SSi

[ Molecular Weight ]:
544.69200

[ Exact Mass ]:
544.17000

[ PSA ]:
144.03000

[ LogP ]:
5.12110

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (2R)-2-[(2S,3S)-3-{(1R)-1-(t-butyldimethylsilyloxy)ethyl}-4-oxoazetidin-2-yl]propionic acid
  • (3S,4S)-1-(tert-butoxycarbonylmethyl)-3-[(1R)-1-tert-butyldimethylsilyloxyethyl]-4-[(1R)-1-carboxyethyl]-2-azetidinone
  • (3S,4S)-1-(tert-butoxycarbonylmethyl)-3-[(1R)-1-tert-butyldimethylsilyloxyethyl]-4-[(1R)-1-phenylthiocarbonylethyl]-2-azetidinone

DownStream

  • Protected meropenem

Related Compounds

  • (R)-1-(thiazol-2-yl)piperidin-3-ol
  • (2R)-6-(3-Formylphenoxy)-2-hydroxyhexyl dodecanoate
  • (2R)-6-(3-Formylphenoxy)-2-hydroxyhexyl decanoate
  • 6-Fluoro-2-(piperidin-3-yl)-1,3-benzoxazole hydrochloride
  • N-(2-aminoethyl)-5-chlorothiophene-2-sulfonamide hydrochloride
  • L-Cysteinyl-L-prolyl-L-tryptophyl-L-valyl-N~5~-(diaminomethylidene)-L-ornithyl-L-asparaginyl-L-valine
  • L-Leucyl-L-prolyl-L-cysteinyl-L-methionyl-L-serine
  • L-Prolyl-N~5~-(diaminomethylidene)-L-ornithyl-N~5~-(diaminomethylidene)-L-ornithyl-L-leucyl-L-leucyl-L-glutaminyl-L-leucine
  • {4-[(Dimethylamino)methyl]-3-fluorophenyl}boronic acid hydrochloride
  • 1-amino-N-[3-(dimethylamino)propyl]cyclohexane-1-carboxamide dihydrochloride
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