(3S,4S)-1-(p-nitrobenzyloxycarbonylmethyl)-4-[(1R)-1-phenylthiocarbonylethyl]-3-[(1R)-1-trimethylsilyloxyethyl]-2-azetidinone

Names

[ CAS No. ]:
105318-32-9

[ Name ]:
(3S,4S)-1-(p-nitrobenzyloxycarbonylmethyl)-4-[(1R)-1-phenylthiocarbonylethyl]-3-[(1R)-1-trimethylsilyloxyethyl]-2-azetidinone

[Synonym ]:
(3S,4S)-3-[(1R)-1-trimethylsilyloxyethyl]-4-[(1R)-1-phenylthiocarbonylethyl]-1-(p-nitrobenzyloxycarbonylmethyl]azetidin-2-one

Chemical & Physical Properties

[ Molecular Formula ]:
C26H32N2O7SSi

[ Molecular Weight ]:
544.69200

[ Exact Mass ]:
544.17000

[ PSA ]:
144.03000

[ LogP ]:
5.12110

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (2R)-2-[(2S,3S)-3-{(1R)-1-(t-butyldimethylsilyloxy)ethyl}-4-oxoazetidin-2-yl]propionic acid
  • (3S,4S)-1-(tert-butoxycarbonylmethyl)-3-[(1R)-1-tert-butyldimethylsilyloxyethyl]-4-[(1R)-1-carboxyethyl]-2-azetidinone
  • (3S,4S)-1-(tert-butoxycarbonylmethyl)-3-[(1R)-1-tert-butyldimethylsilyloxyethyl]-4-[(1R)-1-phenylthiocarbonylethyl]-2-azetidinone

DownStream

  • Protected meropenem

Related Compounds

  • 2-(1-Bromo-2-oxopropyl)-6-methoxybenzonitrile
  • Tert-butyl2-[(fluorosulfonyl)methyl]pyrrolidine-1-carboxylate
  • 2-(1-Bromo-2-oxopropyl)-4-methoxybenzonitrile
  • 2-(1-Bromo-2-oxopropyl)-3-methoxybenzonitrile
  • 2-(1-Bromo-2-oxopropyl)-5-methoxybenzonitrile
  • (R)-8-Fluoro-5-methylchromane-3-carboxylic acid
  • 4-Fluorocyclopent-2-en-1-amine
  • 6-Fluoro-1-azaspiro[3.3]heptane
  • 8-Fluoro-5|E-thia-2-azaspiro[3.4]octane-5,5-dione
  • 2-Bromo-5-chloropyridine-3-sulfonamide
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