(3S,4S)-1-(p-nitrobenzyloxycarbonylmethyl)-4-[(1R)-1-phenylthiocarbonylethyl]-3-[(1R)-1-trimethylsilyloxyethyl]-2-azetidinone

Names

[ CAS No. ]:
105318-32-9

[ Name ]:
(3S,4S)-1-(p-nitrobenzyloxycarbonylmethyl)-4-[(1R)-1-phenylthiocarbonylethyl]-3-[(1R)-1-trimethylsilyloxyethyl]-2-azetidinone

[Synonym ]:
(3S,4S)-3-[(1R)-1-trimethylsilyloxyethyl]-4-[(1R)-1-phenylthiocarbonylethyl]-1-(p-nitrobenzyloxycarbonylmethyl]azetidin-2-one

Chemical & Physical Properties

[ Molecular Formula ]:
C26H32N2O7SSi

[ Molecular Weight ]:
544.69200

[ Exact Mass ]:
544.17000

[ PSA ]:
144.03000

[ LogP ]:
5.12110

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (2R)-2-[(2S,3S)-3-{(1R)-1-(t-butyldimethylsilyloxy)ethyl}-4-oxoazetidin-2-yl]propionic acid
  • (3S,4S)-1-(tert-butoxycarbonylmethyl)-3-[(1R)-1-tert-butyldimethylsilyloxyethyl]-4-[(1R)-1-carboxyethyl]-2-azetidinone
  • (3S,4S)-1-(tert-butoxycarbonylmethyl)-3-[(1R)-1-tert-butyldimethylsilyloxyethyl]-4-[(1R)-1-phenylthiocarbonylethyl]-2-azetidinone

DownStream

  • Protected meropenem

Related Compounds

  • 2-[(Ethylcarbamoyl)amino]-2-oxo-1-phenylethyl 3-hydroxybenzoate
  • 1-(2,5-Dimethylphenyl)-1-oxopropan-2-yl 2-(methylsulfanyl)pyridine-3-carboxylate
  • 1-(3,4-Dimethylphenyl)-1-oxopropan-2-yl 2-(methylsulfanyl)pyridine-3-carboxylate
  • 1-(4-Ethoxyphenyl)-1-oxopropan-2-yl 2-(methylsulfanyl)pyridine-3-carboxylate
  • 2-Fluoro-N-(2-(pyridin-2-yl)ethyl)benzamide
  • N-(3-methoxypropyl)tetrazolo[1,5-b]pyridazin-6-amine
  • [(1-Cyano-1,2-dimethylpropyl)carbamoyl]methyl 2-(4-methoxyphenoxy)acetate
  • [(1-Cyano-1,2-dimethylpropyl)carbamoyl]methyl 2-(3-methylphenoxy)acetate
  • (R)-Oxiranepropanoic acid methyl ester
  • N-(4-Cyanobenzyl)picolinamide
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