5-O-ethyl 3-O-methyl (4R)-4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

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Names

[ CAS No. ]:
105618-03-9

[ Name ]:
5-O-ethyl 3-O-methyl (4R)-4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

[Synonym ]:
Lopac-F-9677

Chemical & Physical Properties

[ Density]:
1.277g/cm3

[ Boiling Point ]:
471.5ºC at 760mmHg

[ Molecular Formula ]:
C18H19Cl2NO4

[ Molecular Weight ]:
384.25400

[ Flash Point ]:
239ºC

[ Exact Mass ]:
383.06900

[ PSA ]:
64.63000

[ LogP ]:
4.29310

[ Vapour Pressure ]:
4.62E-09mmHg at 25°C

[ Index of Refraction ]:
1.549

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • methyl iodide
  • (R)-3-ethyl 5-((R)-1-hydroxy-3-(phenylthio)propan-2-yl) 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
  • Sodium Methylate
  • (2R)-1-(phenylthio)-3-(tetrahydro-2H-pyran-2-yloxy)propan-2-yl 2-(2,3-dichlorobenzylidene)-3-oxobutanoate
  • (4S)-3-ethyl 5-(1-(phenylthio)-3-(tetrahydro-2H-pyran-2-yloxy)propan-2-yl) 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
  • (S)-4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-5-pivaloyloxymethoxycarbonyl-3-pyridinecarboxylic acid
  • (R)-(+)-4-(2,3-dichlorophenyl)-1,4-dihydro-5-methoxycarbonyl-2,6-dimethyl-3-pyridinecarboxylic acid

DownStream

Related Compounds

  • 2-{[4-(Aminomethyl)-1-methylpiperidin-4-yl]oxy}ethan-1-ol
  • (3R)-3-amino-3-{pyrazolo[1,5-a]pyridin-3-yl}propan-1-ol
  • (3R)-3-amino-3-[1-(propan-2-yl)-1H-pyrazol-4-yl]propan-1-ol
  • 2-{[4-(Aminomethyl)-1-methylazepan-4-yl]oxy}ethan-1-ol
  • 2-{[1-Amino-2-(oxan-4-yl)propan-2-yl]oxy}ethan-1-ol
  • 1-[5-Hydroxy-2-(2-methylbutan-2-yl)cyclohexyl]imidazolidin-2-one
  • 3-[(2,2-Dimethylpropyl)(ethyl)amino]-4-methylcyclohexan-1-ol
  • 3-[(2-Methanesulfonylethyl)(methyl)amino]-4-methylcyclohexan-1-ol
  • 4-ethyl-3-[4-(propan-2-yl)-1H-pyrazol-1-yl]cyclohexan-1-ol
  • 4-Tert-butyl-3-[(2-methylpropyl)(propan-2-yl)amino]cyclohexan-1-ol
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