HEPZIDINE MALEATE

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Names

[ CAS No. ]:
1057-81-4

[ Name ]:
HEPZIDINE MALEATE

[Synonym ]:
Hepzidine maleate
BS 7051

Chemical & Physical Properties

[ Boiling Point ]:
417.4ºC at 760 mmHg

[ Molecular Formula ]:
C₂₅H₂₉NO₅

[ Molecular Weight ]:
423.50100

[ Flash Point ]:
122.5ºC

[ Exact Mass ]:
423.20500

[ PSA ]:
87.07000

[ LogP ]:
3.63510

[ Vapour Pressure ]:
3.56E-07mmHg at 25°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TM7175000

CAS REGISTRY NUMBER :: 1057-81-4

LAST UPDATED :: 198512

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C21-H25-N-O.C4-H4-O4

MOLECULAR WEIGHT :: 423.55

WISWESSER LINE NOTATION :: L C676&T&J BO- DT6NTJ A1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 167,334,1967

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 37 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 162,497,1966

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 306 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 167,334,1967

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 102 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 167,334,1967

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 156 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 167,334,1967

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 30 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 16,1342,1966

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 588 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 167,334,1967

Safety Information

[ HS Code ]:
2933399090

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

Hepzidine
TPN729 maleate
Pimethixene maleate
AMlodipine Maleate
trimebutine maleate
PROPIOPROMAZINE MALEATE
(2S)-3-azido-2-(2,2,2-trifluoroacetamido)propanoic acid
3,3-Difluoro-2-(2,2,2-trifluoroacetamido)butanoic acid
6-(2,2,2-Trifluoroacetamido)pyrimidine-4-carboxylic acid
6-(2,2,2-Trifluoroacetamido)pyrazine-2-carboxylic acid
4-(2,2,2-Trifluoroacetamido)pyrimidine-5-carboxylic acid
N-[1-(azetidin-3-yl)-1H-pyrazol-5-yl]-2-methylpyrrolidine-3-carboxamide
6-bromo-2-(difluoromethyl)-3-iodo-2H-indazole
rac-benzyl N-[(1R,2R,4R,5R)-5-(hydroxymethyl)bicyclo[2.2.1]heptan-2-yl]carbamate
5-[3-(2,2,2-Trifluoroacetamido)propyl]pyridine-3-carboxylic acid
benzyl N-(3-nitro-1H-pyrazol-4-yl)carbamate

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