HEPZIDINE MALEATE

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Names

[ CAS No. ]:
1057-81-4

[ Name ]:
HEPZIDINE MALEATE

[Synonym ]:
Hepzidine maleate
BS 7051

Chemical & Physical Properties

[ Boiling Point ]:
417.4ºC at 760 mmHg

[ Molecular Formula ]:
C₂₅H₂₉NO₅

[ Molecular Weight ]:
423.50100

[ Flash Point ]:
122.5ºC

[ Exact Mass ]:
423.20500

[ PSA ]:
87.07000

[ LogP ]:
3.63510

[ Vapour Pressure ]:
3.56E-07mmHg at 25°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TM7175000

CAS REGISTRY NUMBER :: 1057-81-4

LAST UPDATED :: 198512

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C21-H25-N-O.C4-H4-O4

MOLECULAR WEIGHT :: 423.55

WISWESSER LINE NOTATION :: L C676&T&J BO- DT6NTJ A1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 167,334,1967

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 37 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 162,497,1966

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 306 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 167,334,1967

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 102 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 167,334,1967

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 156 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 167,334,1967

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 30 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 16,1342,1966

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 588 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 167,334,1967

Safety Information

[ HS Code ]:
2933399090

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

Hepzidine
TPN729 maleate
Pimethixene maleate
AMlodipine Maleate
trimebutine maleate
PROPIOPROMAZINE MALEATE
4-Hydroxy-1h-pyrazole-3-carboxylic acid
6-(2-Aminoethyl)pyridin-2(1H)-one
n-[1-(4-Bromophenyl)-4-(2-methylphenyl)-4-oxobutyl]acetamide
4-Fluoro-3-cyclohexene-1-methanamine
3-Iodo-5-(trifluoromethyl)benzamide
1,3,4-Oxadiazole, 2,2a(2),2a(2)a(2),2a(2)a(2)a(2)-[1,1a(2)-biphenyl]-3,3a(2),5,5a(2)-tetrayltetrakis[5-[4-(1,1-dimethylethyl)phenyl]-
4-(1H-imidazol-2-yl)-2-methylaniline
Methyl 4-(2-hydroxyethoxy)cyclohexanecarboxylate
4-methyl-1-(pyridin-2-yl)-1H-pyrazol-3-amine
2-[Bis(2-hydroxyethyl)amino]-2-propanol

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