4-Thiazolidinone,3-(phenylmethyl)-2-thioxo-

Suppliers

Names

[ CAS No. ]:
10574-69-3

[ Name ]:
4-Thiazolidinone,3-(phenylmethyl)-2-thioxo-

[Synonym ]:
3-Benzyl-2-thioxo-4-thiazolidinone
3-benzyl-2-sulfanylidene-1,3-thiazolidin-4-one

Chemical & Physical Properties

[ Density]:
1.39g/cm3

[ Boiling Point ]:
353ºC at 760mmHg

[ Melting Point ]:
89ºC

[ Molecular Formula ]:
C10H9NOS2

[ Molecular Weight ]:
223.31500

[ Flash Point ]:
167.3ºC

[ Exact Mass ]:
223.01300

[ PSA ]:
77.70000

[ LogP ]:
1.98480

[ Vapour Pressure ]:
3.7E-05mmHg at 25°C

[ Index of Refraction ]:
1.707

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VI7800000
CHEMICAL NAME :
Rhodanine, 3-benzyl-
CAS REGISTRY NUMBER :
10574-69-3
BEILSTEIN REFERENCE NO. :
0155718
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C10-H9-N-O-S2
MOLECULAR WEIGHT :
223.32

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 19,558,1969
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 21,121,1971

Safety Information

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-36/37/39

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Carbon disulphide
  • Chloroacetic acid
  • Benzylamine
  • Acetic acid,2,2'-[carbonothioylbis(thio)]bis-
  • Bromoacetic acid
  • Rhodanine
  • Benzyl alcohol
  • ethyl 2-bromoacetate
  • a-Isothiocyanatotoluene
  • Methyl thioglycolate

DownStream

  • (5E)-3-benzyl-5-[(4-chlorophenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one
  • (5E)-3-benzyl-5-benzylidene-2-sulfanylidene-1,3-thiazolidin-4-one

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 4-Thiazolidinone,3-(phenylmethyl)-2-propyl-
  • 3-[(4-methylphenyl)-phenylmethyl]-2-sulfanylidene-1,3-thiazolidin-4-one
  • 3-[(4-methoxyphenyl)-phenylmethyl]-2-sulfanylidene-1,3-thiazolidin-4-one
  • 3-[(2,4-dimethylphenyl)-phenylmethyl]-2-sulfanylidene-1,3-thiazolidin-4-one
  • 3-[(3,4-dimethylphenyl)-phenylmethyl]-2-sulfanylidene-1,3-thiazolidin-4-one
  • 3-[(4-chlorophenyl)-phenylmethyl]-2-sulfanylidene-1,3-thiazolidin-4-one