4-Bromotoluene

Names

[ CAS No. ]:
106-38-7

[ Name ]:
4-Bromotoluene

[Synonym ]:
MFCD00000109
Benzene, 1-bromo-4-methyl-
4-tolyl bromide
p-Bromotoluene
1-Bromo-4-methylbenzene
EINECS 203-391-8
4-Bromotoluene

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
183.8±9.0 °C at 760 mmHg

[ Melting Point ]:
26-29 °C(lit.)

[ Molecular Formula ]:
C₇H₇Br

[ Molecular Weight ]:
171.035

[ Flash Point ]:
85.0±0.0 °C

[ Exact Mass ]:
169.973099

[ LogP ]:
3.45

[ Vapour Pressure ]:
1.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.549

[ Water Solubility ]:
<0.1 g/100 mL at 24 ºC

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XS7965600

CHEMICAL NAME :: Toluene, p-bromo-

CAS REGISTRY NUMBER :: 106-38-7

LAST UPDATED :: 199710

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C7-H7-Br

MOLECULAR WEIGHT :: 171.05

WISWESSER LINE NOTATION :: ER D1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1741 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 20(12),52,1976

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: 1300 mg/m3

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 18(4),55,1974

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R22;R36/37/38

[ Safety Phrases ]:
S28-S61-S37/39-S26

[ RIDADR ]:
UN 3077 9/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
XS7965600

[ Hazard Class ]:
9.0

[ HS Code ]:
29036990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Toluene
4-Tolylboronic acid
4-Bromobenzyl bromide
4-methylbenzenediazonium tetrafluoroborate
phenetole
4-Iodotoluene
4-Bromobenzaldehyde
4-Bromobenzyl alcohol
4-Chlorotoluene
2-(p-bromophenyl)-1,3-Dithiolane

DownStream

(4-bromophenyl)methyl 4-bromobenzoate
4-Bromobenzoic acid
4-Bromobenzyl alcohol
4-Bromobenzaldehyde
2-(4-methylphenyl)-1-phenylpropan-1-one
Phenyl ethyl ketone
2-[3-(4-methylphenyl)propyl]furan
1-butoxy-4-methylbenzene
2-Pentanone,4-methyl-4-(4-methylphenyl)-
Diethyl 4-Bromobenzylphosphonate

Customs

[ HS Code ]: 2903999090

[ Summary ]:
2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

Tetragonal Cu2Se nanoflakes: synthesis using selenated propylamine as Se source and activation of Suzuki and Sonogashira cross coupling reactions.

Dalton Trans. 44(2) , 725-32, (2014)

The metastable tetragonal Cu2Se phase as nanoflakes has been synthesized for the first time by treating CuCl2 taken in a mixture (1:1) of 1-octadecene and oleylamine with H2N-(CH2)3-SePh dissolved in ...

Possible intermediates of Cu(phen)-catalyzed C-O cross-coupling of phenol with an aryl bromide by in situ ESI-MS and EPR studies.

Dalton Trans. 43(29) , 11410-7, (2014)

The C-O coupling reaction between 2,4-dimethylphenol and 4-bromotoluene catalyzed by the CuI/K2CO3/phen system can be inhibited by the radical scavenger cumene. Complexes [Cu(i)(phen)(1-(2,4-dimethylp...

Fluorogenic derivatization of aryl halides based on the formation of biphenyl by Suzuki coupling reaction with phenylboronic acid

J. Chromatogr. A. 1216(40) , 6873-6, (2009)

The fluorogenic derivatization method for aryl halide was developed for the first time. This method was based on the formation of fluorescent biphenyl structure by Suzuki coupling reaction between ary...

2,4-bromotoluene
4-Bromotoluene-d3
4-bromotoluene-d7
2-nitro-4-bromotoluene
2-Amino-4-bromotoluene
2-FLUORO-4-BROMOTOLUENE
5-(chloromethyl)-1,3-dimethylpyrimidine-2,4(1H,3H)-dione
3-((5-((2,5-dimethylbenzyl)thio)-4-(o-tolyl)-4H-1,2,4-triazol-3-yl)methyl)benzo[d]thiazol-2(3H)-one
3-((5-((4-methylbenzyl)thio)-4-(o-tolyl)-4H-1,2,4-triazol-3-yl)methyl)benzo[d]thiazol-2(3H)-one
3-((5-((2-fluorobenzyl)thio)-4-(o-tolyl)-4H-1,2,4-triazol-3-yl)methyl)benzo[d]thiazol-2(3H)-one
3-((5-(sec-butylthio)-4-(4-methoxyphenyl)-4H-1,2,4-triazol-3-yl)methyl)benzo[d]thiazol-2(3H)-one
3-((4-(4-methoxyphenyl)-5-((pyridin-2-ylmethyl)thio)-4H-1,2,4-triazol-3-yl)methyl)benzo[d]thiazol-2(3H)-one
3-((4-(3-chlorophenyl)-5-((2-oxo-2-(pyrrolidin-1-yl)ethyl)thio)-4H-1,2,4-triazol-3-yl)methyl)benzo[d]thiazol-2(3H)-one
1-(4-phenoxyphenyl)-3-[2-(2-pyrrolidin-1-ylethyl)-2H-indazol-5-yl]-1,3-dihydro-2H-imidazol-2-one
1,8-Dibromooctane-2,7-dione
N-(benzo[d][1,3]dioxol-5-yl)-2-((5-((2-oxobenzo[d]thiazol-3(2H)-yl)methyl)-4-(3-(trifluoromethyl)phenyl)-4H-1,2,4-triazol-3-yl)thio)acetamide

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