2,5-Dimethylpiperazine

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Names

[ CAS No. ]:
106-55-8

[ Name ]:
2,5-Dimethylpiperazine

[Synonym ]:
2,4-DINITRO-5-FLUOROTOLUENE
2,5-dimethyl piperazine
2,5-trans-methylpiperazine
MFCD00005955
cis,trans-2,5-dimethylpiperazine
UNII-VZG2W7X75O
3,6-dimethylpiperazine
EINECS 203-409-4
cis-2,5-dimethyl piperazine
2,5-Dimethylpiperazine
Piperazine, 2,5-dimethyl-

Chemical & Physical Properties

[ Density]:
0.8±0.1 g/cm3

[ Boiling Point ]:
165.9±8.0 °C at 760 mmHg

[ Melting Point ]:
113-118ºC

[ Molecular Formula ]:
C6H14N2

[ Molecular Weight ]:
114.189

[ Flash Point ]:
58.3±0.0 °C

[ Exact Mass ]:
114.115700

[ PSA ]:
24.06000

[ LogP ]:
-0.19

[ Vapour Pressure ]:
1.8±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.413

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TL5950000
CHEMICAL NAME :
Piperazine, 2,5-dimethyl-
CAS REGISTRY NUMBER :
106-55-8
BEILSTEIN REFERENCE NO. :
0079885
LAST UPDATED :
199806
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C6-H14-N2
MOLECULAR WEIGHT :
114.22
WISWESSER LINE NOTATION :
T6M DMTJ B1 E1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3160 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 4,119,1951
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
800 uL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 4,119,1951

Safety Information

[ Hazard Codes ]:
F: Flammable;C: Corrosive;

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
45-36/37/39-26-16

[ HS Code ]:
2933599090

Synthetic Route

Precursor & DownStream

Precursor

  • 1,4-Dioxane
  • Amino-2-propanol
  • D-(+)-Glucose
  • Sorbitol
  • Carbon dioxide
  • 2-Methylaziridine
  • Glycerol
  • Propylene Glycol
  • Ammonia

DownStream

  • 1-Piperazineethanamine,-alpha-,2,5-trimethyl-(9CI)
  • 1-Piperazineethanamine,-bta-,2,5-trimethyl-(9CI)
  • 2,5-Dimethylpyrazine

Customs

[ HS Code ]: 2933599090

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%


Related Compounds

  • 2,5-Dimethylpiperazine
  • cis-2,5-dimethylpiperazine
  • CIS-2,5-DIMETHYLPIPERAZINE
  • (2S,5S)-2,5-dimethylpiperazine
  • 1-ethyl-2,5-dimethylpiperazine
  • 3-Butyl-2,5-dimethylpiperazine
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • (2R)-1-(6-bromopyridin-3-yl)propan-2-ol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide