N,N'-Dimethylpiperazine

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Names

[ CAS No. ]:
106-58-1

[ Name ]:
N,N'-Dimethylpiperazine

[Synonym ]:
1,4-N,N'-dimethylpiperazine
EINECS 203-412-0
1,4-Dimethylpiperazine
N,N‘-Dimethylpiperazine
Texacat DMP
N,N'-Dimethylpiperazine
N,N′-Dimethylpiperazine
N,N-Dimethylpiperazine
MFCD00006156
N,N'-Dimethyipiperazine
N,N'-dimethyl-piperazine
1,4-dimethyl-1,4-diazacyclohexane
1,4-dimethyl-piperazine
Piperazine, 1,4-dimethyl-
N,N'-Dimethylpiperaz
Lupetazine
1,4-dimethyl-piperazin

Chemical & Physical Properties

[ Density]:
0.844

[ Boiling Point ]:
130-133 ºC

[ Melting Point ]:
-1 °C

[ Molecular Formula ]:
C6H14N2

[ Molecular Weight ]:
114.189

[ Flash Point ]:
21.5 ºC

[ Exact Mass ]:
114.115700

[ PSA ]:
6.48000

[ LogP ]:
-0.61

[ Vapour Pressure ]:
7.5±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.457

[ Storage condition ]:
Flammables area

[ Water Solubility ]:
miscible

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TL5945000
CHEMICAL NAME :
Piperazine, 1,4-dimethyl-
CAS REGISTRY NUMBER :
106-58-1
LAST UPDATED :
199709
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C6-H14-N2
MOLECULAR WEIGHT :
114.22
WISWESSER LINE NOTATION :
T6N DNTJ A1 D1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2500 mg/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Lungs, Thorax, or Respiration - dyspnea Lungs, Thorax, or Respiration - other changes
REFERENCE :
THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 9,314,1954

Safety Information

[ Symbol ]:

GHS02, GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H314

[ Precautionary Statements ]:
P210-P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
C:Corrosive;

[ Risk Phrases ]:
R10;R22;R34

[ Safety Phrases ]:
S16-S26-S27-S36/37/39-S45-S25-S23

[ RIDADR ]:
UN 2924 3/PG 2

[ WGK Germany ]:
1

[ RTECS ]:
TL5945000

[ Packaging Group ]:
II

[ Hazard Class ]:
3

[ HS Code ]:
29335995

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • TMEDA
  • Methanol
  • 2-(2-Aminoethylamino)ethanol
  • methylpiperazine
  • Piperazine
  • Formaldehyde
  • methyl 4-methylpiperazine-1-carboxylate
  • Glycine Anhydride
  • dea
  • methylamine

DownStream

  • α-Cumyl alcohol
  • 1,1,4,4-tetramethylpiperazine-1,4-diium,dibromide
  • 1,4-dimethyl-1,4-dioxidopiperazine-1,4-diium
  • N,N'-Dinitrosopiperazine
  • 1-ethyl-1,4-dimethylpiperazin-1-ium,iodide
  • Piperazinium,1,1,4,4-tetramethyl-, iodide (1:2)
  • 1,1,4,4-tetramethyl-2,3,5,6-tetrahydropyrazine
  • 1,4-dimethyl-1,4-diazoniabicyclo[2.2.2]octane,dibromide
  • Benzyl alcohol

Customs

[ HS Code ]: 2933599090

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 2-methyl-N,N'-dimethylpiperazine
  • N,N'-dimethylpiperazine-2,3-dithione
  • N,N'-dimethylpiperazine-2,3-dithione
  • ethyl N,N'-dimethylpiperazine-2-carboxylate
  • Bis(N,N'-dimethylpiperazine)tetra[copper(I) iodide]
  • N,N'-Dimethyldiketopiperazine
  • 2-{1-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methyloxolan-3-yl]-N-(prop-2-en-1-yl)formamido}acetic acid
  • 2-{[(Benzyloxy)carbonyl]amino}-4-(oxan-4-yl)butanoic acid
  • 4-Methyl-1-{[5-(2-methylpropyl)pyridin-3-yl]sulfanyl}pentan-2-one
  • 2-({[5-(2-Methylpropyl)pyridin-3-yl]sulfanyl}methyl)-1,4,5,6-tetrahydropyrimidine
  • 5-[Cyclobutyl(prop-2-yn-1-yl)amino]furan-2-carboxylic acid
  • 1-(2-Methylcyclopropyl)-2-{[5-(2-methylpropyl)pyridin-3-yl]sulfanyl}ethan-1-one
  • 1-{2-[1-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)ethyl]-1,3-thiazole-4-amido}cyclopropane-1-carboxylic acid
  • 5-(3-Ethynylpiperidin-1-yl)furan-2-carboxylic acid
  • 3-Fluoro-2-[(4-hydroxybut-2-yn-1-yl)amino]benzoic acid
  • Tert-butyl 4-hydroxy-4-[3-(hydroxymethyl)oxan-3-yl]piperidine-1-carboxylate