2-Amino-4-(trifluoromethyl)pyridine

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Names

[ CAS No. ]:
106447-97-6

[ Name ]:
2-Amino-4-(trifluoromethyl)pyridine

[Synonym ]:
MFCD00077455
2-Pyridinamine, 4-(trifluoromethyl)-
4-(Trifluoromethyl)pyridin-2-amine
2-Amino-4-(trifluoromethyl)pyridine
4-(Trifluoromethyl)-2-pyridinamine

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
221.3±40.0 °C at 760 mmHg

[ Melting Point ]:
70-74 °C

[ Molecular Formula ]:
C6H5F3N2

[ Molecular Weight ]:
162.11

[ Flash Point ]:
87.7±27.3 °C

[ Exact Mass ]:
162.040482

[ PSA ]:
38.91000

[ LogP ]:
2.07

[ Vapour Pressure ]:
0.1±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.479

[ Storage condition ]:
Room temperature.

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H300-H315-H317-H319-H335

[ Precautionary Statements ]:
P261-P264-P280-P301 + P310-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ Hazard Codes ]:
T,Xi

[ Risk Phrases ]:
R23/24/25;R36/37/38

[ Safety Phrases ]:
S26-S36/37-S45

[ RIDADR ]:
UN 2811 6.1/PG 3

[ WGK Germany ]:
3

[ Packaging Group ]:
II

[ Hazard Class ]:
6.1

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 5-ethoxy-3-hydroxy-3-(trifluoromethyl)pent-4-enenitrile
  • 5-Bromo-4-(trifluoromethyl)pyridin-2-amine
  • Bis(pinacolato)diboron
  • 2,6-Dichloro-4-trifluoromethylpyridine
  • 2-Chloro-4-(trifluoromethyl)pyridine
  • 4-(Trifluoromethyl)pyridine 1-oxide

DownStream

  • 2-Hydroxy-4-(trifluoromethyl)pyridine
  • 5-Bromo-4-(trifluoromethyl)pyridin-2-amine
  • NVP-BKM120 (Hydrochloride)
  • 5-Chloro-4-(trifluoromethyl)pyridin-2-amine
  • 4-(Trifluoromethyl)pyridine-2-thiol
  • phenyl (4-(trifluoromethyl)pyridin-2-yl)carbamate

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 2-Amino-4-(trifluoromethyl)pyridine
  • 2-amino-4-(trifluoromethyl)pyridine-3-carboxylic acid
  • 2-amino-4,6-bis(trifluoromethyl)pyridine-3-carbonitrile
  • 2-amino-4,6-bis(trifluoromethyl)pyridine-3-carbohydrazide
  • 2-amino-4,6-bis(trifluoromethyl)pyridine-3-carboxamide
  • 4-Iodo-5-(trifluoromethyl)pyridin-2-amine
  • 2-(2,3-dihydro-1H-inden-5-yl)-2-fluoroacetic acid
  • 3-Methyl-1-(1-naphthalenyloxy)-2-butanamine
  • 1-(2-Amino-3-methylbutoxy)-2,4-difluorobenzene
  • 2-(1-Aminopropan-2-yl)bicyclo[2.2.1]heptan-2-ol
  • 2'H-Spiro[bicyclo[2.2.1]heptane-2,3'-[1,4]oxazole]-5'-amine
  • 1-[(2-Amino-3-methylpentyl)oxy]-2-fluorobenzene
  • 1-(2-Amino-3-methylbutoxy)-2-fluorobenzene
  • 3-Amino-2-(3-hydroxy-4-methylphenyl)propanoic acid
  • 1-(1H-1,2,4-triazol-3-yl)cyclohexane-1-carboxylic acid
  • 4-(1H-1,2,4-triazol-5-yl)cyclohexane-1-carboxylic acid
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