Methyl 4-bromo-2-chloronicotinate

Names

[ Name ]:
Methyl 4-bromo-2-chloronicotinate

[Synonym ]:
N,N-Dimethyl 4-bromo-2-chlorobenzamide
4-bromo-2-chloro-nicotinic acid methyl ester
4-bromo-2-chloro-N,N-dimethyl-benzamide
Methyl 4-bromo-2-chloropyridine-3-carboxylate

Chemical & Physical Properties

[ Melting Point ]:
54-58°C

[ Molecular Formula ]:
C₇H₅BrClNO₂

[ Molecular Weight ]:
250.47700

[ Exact Mass ]:
248.91900

[ PSA ]:
39.19000

[ LogP ]:
2.28410

MSDS

Safety Information

[ Symbol ]:

GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H400

[ Precautionary Statements ]:
P273

[ Hazard Codes ]:
N

[ RIDADR ]:
UN 3077 9 / PGIII

Synthetic Route

Click to get detail synthetic route

Articles

Novel small molecule bradykinin B2 receptor antagonists.

J. Med. Chem. 14th ed., 52 , 4370-4379, (2009)

Blockade of the bradykinin B(2) receptor provides therapeutic benefit in hereditary angioedema (HAE) and potentially in many other diseases. Herein, we describe the development of highly potent B(2) r...

Methyl (4-bromo-2-methyl-6-nitrophenoxy)acetate
methyl 4-bromo-2-chloro-5-nitrobenzoate
Methyl 4-bromo-2-(cyanomethyl)benzoate
Methyl 4-bromo-2-(bromomethyl)-6-chlorobenzoate
Methyl 4-bromo-2-chlorobenzoate
methyl 4-bromo-2,3-dimethoxybenzoate