5'-O-(isopropyl-L-alanate,phenyl-phosphoramidyl)-2'-deoxy-2'-fluoro-2'-C-methyl-uridine

Names

[ CAS No. ]:
1064684-44-1

[ Name ]:
5'-O-(isopropyl-L-alanate,phenyl-phosphoramidyl)-2'-deoxy-2'-fluoro-2'-C-methyl-uridine

[Synonym ]:
2''-deoxy-2''-

Chemical & Physical Properties

[ Molecular Formula ]:
C22H29FN3O9P

[ Molecular Weight ]:
529.45300

[ Exact Mass ]:
529.16300

[ PSA ]:
167.99000

[ LogP ]:
2.04740

Synthetic Route

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Precursor & DownStream

Precursor

  • PSI-6206
  • Phenyl dichlorophosphate
  • D-Alanine isopropyl ester hydrochloride
  • L-Alanine, N-[(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-, 1-Methylethyl ester

DownStream

  • Sofosbuvir