((3-(bis(2-chloroethyl)amino)-4-methylphenyl)hydroxymethane)bisphosphonic acid

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Names

[ CAS No. ]:
106871-13-0

[ Name ]:
((3-(bis(2-chloroethyl)amino)-4-methylphenyl)hydroxymethane)bisphosphonic acid

Chemical & Physical Properties

[ Density]:
1.672g/cm3

[ Boiling Point ]:
720.3ºC at 760mmHg

[ Molecular Formula ]:
C12H19Cl2NO7P2

[ Molecular Weight ]:
422.13500

[ Flash Point ]:
389.4ºC

[ Exact Mass ]:
421.00100

[ PSA ]:
158.15000

[ LogP ]:
1.73700

[ Vapour Pressure ]:
8.98E-22mmHg at 25°C

[ Index of Refraction ]:
1.633

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SZ6790000
CHEMICAL NAME :
Phosphonic acid, ((3-(bis(2-chloroethyl)amino)-4-methylphenyl)hydroxym ethylene)bis-
CAS REGISTRY NUMBER :
106871-13-0
LAST UPDATED :
199410
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C12-H19-Cl2-N-O7-P2
MOLECULAR WEIGHT :
422.16

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
88 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
DNA damage
TEST SYSTEM :
Rodent - hamster Embryo
DOSE/DURATION :
1250 ug/plate
REFERENCE :
INNDDK Investigational New Drugs. The Journal of New Anticancer Agents. Kluwer Academic Pub., POB 358, Accord Stn., Hingham, MA 02018) V.1- 1983- Volume(issue)/page/year: 6,67,1988

Related Compounds

  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-(2,4-dimethylthiazol-5-yl)-N-(quinolin-5-yl)acetamide
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide