tert-Butyl chloroacetate
Suppliers
Names
[ CAS No. ]:
107-59-5
[ Name ]:
tert-Butyl chloroacetate
[Synonym ]:
Acetic acid, 2-chloro-, 1,1-dimethylethyl ester
MFCD00000930
Acetic acid, chloro-, tert-butyl ester (8CI)
EINECS 203-506-1
2-Methyl-2-propanyl chloroacetate
tert-Butyl chloroacetate
tert-butyl 2-chloroacetate
Chloroacetic acid tert-Butyl Ester
TERT-BUTYLCHLOROACETATE
Chemical & Physical Properties
[ Density]:
1.1±0.1 g/cm3
[ Boiling Point ]:
157.5±0.0 °C at 760 mmHg
[ Molecular Formula ]:
C6H11ClO2
[ Molecular Weight ]:
150.603
[ Flash Point ]:
46.7±0.0 °C
[ Exact Mass ]:
150.044754
[ PSA ]:
26.30000
[ LogP ]:
1.64
[ Vapour Pressure ]:
2.8±0.3 mmHg at 25°C
[ Index of Refraction ]:
1.425
[ Storage condition ]:
Flammables area
[ Water Solubility ]:
<0.1 g/L (20 ºC)
MSDS
Safety Information
[ Symbol ]:
GHS02, GHS05, GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H226-H302 + H312-H314-H331
[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338-P310
[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
Xn:Harmful;N:Dangerousfortheenvironment;
[ Risk Phrases ]:
R10;R20/21/22;R36/37/38;R50/53
[ Safety Phrases ]:
S26-S36/37/39-S45-S61-S60-S16
[ RIDADR ]:
UN 2920 8/PG 2
[ WGK Germany ]:
3
[ RTECS ]:
AF8985500
[ Packaging Group ]:
III
[ Hazard Class ]:
3
[ HS Code ]:
29154000
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 29154000
Articles
J. Org. Chem. 65(18) , 5498-505, (2000)
Intermolecular alkylation of the aziridinyl oxazole 20 using PhSO(2)CH(2)CH(2)OTf is possible despite the presence of potentially nucleophilic aziridine nitrogen. The resulting oxazolium salt 22 react...
Beilstein J. Org. Chem. 4 , 42, (2008)
A convenient and practical synthesis of imidazol-1-yl-acetic acid hydrochloride was achieved via N-alkylation of imidazole using tert-butyl chloroacetate followed by a non-aqueous ester cleavage of th...
Substituent dependent fluorescence response of diazacrown-based PET sensors. Nagy K, et al.Tetrahedron 64(27) , 6191-95, (2008)