bis(2-chloroethyl)phosphite

Names

[ CAS No. ]:
1070-42-4

[ Name ]:
bis(2-chloroethyl)phosphite

[Synonym ]:
Phosphorous acid,bis(2-chloroethyl) ester
bis(2-chloroethyl) H-phosphonate
Einecs 213-975-4
Phosphonic acid,bis(2-chloroethyl) ester
bis(2-chloethyl) hydrogen phosphite
Ethanol,2-chloro-,phosphite (2:1)
di(2-chloroethyl)phosphorous acid
2-chloro-ethanophosphite(2:1)
bis(2-chloroethyl) phosphonate

Chemical & Physical Properties

[ Boiling Point ]:
311.5ºC at 760mmHg

[ Molecular Formula ]:
C4H9Cl2O3P

[ Molecular Weight ]:
206.99200

[ Flash Point ]:
142.2ºC

[ Exact Mass ]:
205.96700

[ PSA ]:
52.28000

[ LogP ]:
1.71640

[ Vapour Pressure ]:
0.012mmHg at 25°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KK2800000
CAS REGISTRY NUMBER :
1070-42-4
BEILSTEIN REFERENCE NO. :
1705711
LAST UPDATED :
199612
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C4-H9-Cl2-O3-P
MOLECULAR WEIGHT :
207.00
WISWESSER LINE NOTATION :
G2OPO&O2G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
260 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 30,470,1969
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 7,790,1955
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
141 uL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 30,470,1969 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84167 No. of Facilities: 21 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 21 (estimated)

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-Chloroethanol
  • tris(2-chloroethyl) phosphite
  • Diethyl phosphite
  • Phosphorous acid
  • dichloroethane
  • chloro-bis(2-chloroethoxy)phosphane

DownStream

  • bis(2-chloroethyl) chlorophosphate
  • Phosphonic acid,[hydroxy(3-nitrophenyl)methyl]-, bis(2-chloroethyl) ester (9CI)

Related Compounds

  • bis(2-chloroethyl) 2-(2-chlorophenoxy)ethyl phosphite
  • bis-2-chloroethyl <2-(1-benzimidazolyl)ethyl>phosphonate
  • bis(2-chloroethyl) selenide
  • Bis(2-chloroethyl)aminophosphonic dichloride
  • Bis(2-chloroethyl)aminomethyl-4-hydroxynitrobenzene
  • bis(2-chloroethyl) (2,3,5-trichlorophenyl) phosphate
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • Trans-3-(Boc-amino)cyclobutylpropanoic acid
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • Ethyl 1-hydroxy-3,3-dimethylcyclobutane-1-carboxylate
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine