bis(2-chloroethyl)phosphite

Names

[ CAS No. ]:
1070-42-4

[ Name ]:
bis(2-chloroethyl)phosphite

[Synonym ]:
Phosphorous acid,bis(2-chloroethyl) ester
bis(2-chloroethyl) H-phosphonate
Einecs 213-975-4
Phosphonic acid,bis(2-chloroethyl) ester
bis(2-chloethyl) hydrogen phosphite
Ethanol,2-chloro-,phosphite (2:1)
di(2-chloroethyl)phosphorous acid
2-chloro-ethanophosphite(2:1)
bis(2-chloroethyl) phosphonate

Chemical & Physical Properties

[ Boiling Point ]:
311.5ºC at 760mmHg

[ Molecular Formula ]:
C4H9Cl2O3P

[ Molecular Weight ]:
206.99200

[ Flash Point ]:
142.2ºC

[ Exact Mass ]:
205.96700

[ PSA ]:
52.28000

[ LogP ]:
1.71640

[ Vapour Pressure ]:
0.012mmHg at 25°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KK2800000
CAS REGISTRY NUMBER :
1070-42-4
BEILSTEIN REFERENCE NO. :
1705711
LAST UPDATED :
199612
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C4-H9-Cl2-O3-P
MOLECULAR WEIGHT :
207.00
WISWESSER LINE NOTATION :
G2OPO&O2G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
260 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 30,470,1969
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 7,790,1955
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
141 uL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 30,470,1969 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84167 No. of Facilities: 21 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 21 (estimated)

Synthetic Route

Precursor & DownStream

Precursor

  • 2-Chloroethanol
  • tris(2-chloroethyl) phosphite
  • Diethyl phosphite
  • Phosphorous acid
  • dichloroethane
  • chloro-bis(2-chloroethoxy)phosphane

DownStream

  • bis(2-chloroethyl) chlorophosphate
  • Phosphonic acid,[hydroxy(3-nitrophenyl)methyl]-, bis(2-chloroethyl) ester (9CI)

Related Compounds

  • bis(2-chloroethyl) 2-(2-chlorophenoxy)ethyl phosphite
  • bis-2-chloroethyl <2-(1-benzimidazolyl)ethyl>phosphonate
  • bis(2-chloroethyl) selenide
  • Bis(2-chloroethyl)aminophosphonic dichloride
  • Bis(2-chloroethyl)aminomethyl-4-hydroxynitrobenzene
  • bis(2-chloroethyl) (2,3,5-trichlorophenyl) phosphate
  • 1-(Cyclobutylmethyl)-4-(3-fluoro-4-methylphenyl)piperazine-2,3-dione
  • Ethyl 3-(3-hydroxythiolan-3-yl)thiane-3-carboxylate
  • O-{2-[1-(cyclopropylmethyl)-1H-1,2,3-triazol-4-yl]ethyl}hydroxylamine
  • 4-Amino-4-(but-1-en-1-yl)cyclohexan-1-ol
  • Methyl[2-methyl-1-(2,3,6-trifluorophenyl)propan-2-yl]amine
  • Terephthalimidamide tetrahydrochloride
  • ethyl 4-amino-6-methyl-1H-pyrazolo[3,4-d]pyrimidine-1-carboxylate
  • 3-Methyl-6-[3-(2-methylbenzimidazol-1-yl)azetidin-1-yl]-1,3-diazinane-2,4-dione
  • N-(2-oxo-1,3,3a,4,5,6,7,7a-octahydrobenzimidazol-5-yl)-2-(thiolan-3-yloxy)pyridine-3-carboxamide
  • {1-[2-(4-Fluorophenyl)ethenyl]cyclohexyl}methanamine
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