1,1,1,3-Tetrachloropropane

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Names

[ CAS No. ]:
1070-78-6

[ Name ]:
1,1,1,3-Tetrachloropropane

[Synonym ]:
Propane, 1,1,1,3-tetrachloro-
1,1,1,3-Tetrachloropropane
EINECS 213-981-7
MFCD00054655
1,1,1,3-Tetrachloro-Propane

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
161.3±8.0 °C at 760 mmHg

[ Melting Point ]:
-35 °C

[ Molecular Formula ]:
C3H4Cl4

[ Molecular Weight ]:
181.876

[ Flash Point ]:
51.4±15.8 °C

[ Exact Mass ]:
179.906708

[ LogP ]:
3.18

[ Vapour Pressure ]:
3.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.483

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TZ7000000
CHEMICAL NAME :
Propane, 1,1,1,3-tetrachloro-
CAS REGISTRY NUMBER :
1070-78-6
BEILSTEIN REFERENCE NO. :
1734994
LAST UPDATED :
199710
DATA ITEMS CITED :
9
MOLECULAR FORMULA :
C3-H4-Cl4
MOLECULAR WEIGHT :
181.87
WISWESSER LINE NOTATION :
GXGG2G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
490 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TSCAT* Office of Toxic Substances Report. (U.S. Environmental Protection Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460) Volume(issue)/page/year: OTS0515505
TYPE OF TEST :
LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
4700 ppm/6H
TOXIC EFFECTS :
Behavioral - ataxia
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0520625
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1 mL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0520626
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>2 mL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0520626 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
13650 mg/kg/13W-I
TOXIC EFFECTS :
Blood - other changes Blood - changes in leukocyte (WBC) count
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 27(9),3,1962
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
225 ppm/6H/90D-I
TOXIC EFFECTS :
Cardiac - other changes Liver - hepatitis (hepatocellular necrosis), diffuse Liver - changes in liver weight
REFERENCE :
FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 25,52,1995

Safety Information

[ Hazard Codes ]:
Xi: Irritant;

[ RTECS ]:
TZ7000000

[ HS Code ]:
2903199000

Synthetic Route

Precursor & DownStream

Precursor

  • Carbon tetrachloride
  • ethene
  • Trichloromethanesulfonyl chloride
  • 1,1,1-trichloropropane
  • Water
  • Benzoyl peroxide
  • tetraethyltin
  • 2,2'-Azobis(2-methylpropionitrile)
  • 3,3,3-trichloro-propyl
  • propene

DownStream

  • 3-chloro-1,1,1-trifluoropropane
  • 1,3-Dichloro-1,1-difluoropropane
  • 3,3,3-Trifluoropropene
  • 1,1,3-Trichloropropene
  • 3,3,3-Trichloropropene
  • 1,1,1,2,3-Pentachloropropane
  • 1,1,1,3,3-Pentachloropropane
  • 1,3,3,5-tetrachloropentane
  • 1,3,3,7-tetrachloro-heptane

Customs

[ HS Code ]: 2903199000

[ Summary ]:
2903199000 other saturated chlorinated derivatives of acyclic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%


Related Compounds

  • 2,2-Difluoro-1,1,1,3-tetrachloropropane
  • 1,1,1,3,3,3-hexadeuteriopropane
  • 1-[[1-(1,3-dimethylindol-2-yl)cyclopentyl]methyl]-3-[2,6-di(propan-2-yl)phenyl]urea
  • 1,1,1,3,3,3-hexafluoro-2-[3-(1,1,1,3,3,3-hexafluoro-2-hydroxy-propan-2-yl)-2-iodo-5-methyl-phenyl]propan-2-ol
  • 1,1,1,3,3,3-hexafluoro-2-(1H-indol-2-ylmethyl)propan-2-ol
  • 1,1,1,3,3,3-hexafluoro-2-[(3Z)-3-hydroxyimino-2-bicyclo[2.2.1]heptanyl]propan-2-ol
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 4a(2)-Methoxy[1(2H),2a(2)-bipyridin]-2-one
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • 4-(1,1-Difluoro-2-hydroxyethyl)-2-methoxy-6-nitrophenol
  • tert-Butyl-DL-alanine