Zafirlukast

Suppliers

Names

[ Name ]:
Zafirlukast

[Synonym ]:
Cyclopentyl [3-(2-methoxy-4-{[(2-methylphenyl)sulfonyl]carbamoyl}benzyl)-1-methyl-1H-indol-5-yl]carbamate
Vanticon
Accoleit
Cyclopentyl [3-[2-Methoxy-4-[(o-tolylsulfonyl)carbamoyl]benzyl]-1-methyl-1H-indol-5-yl]carbamate
carbamic acid, [3-[[2-methoxy-4-[[[(2-methylphenyl)sulfonyl]amino]carbonyl]phenyl]methyl]-1-methyl-1H-indol-5-yl]-, cyclopentyl ester
Cyclopentyl 3-[2-methoxy-4-({[(2-methylphenyl)sulfonyl]amino}carbonyl)benzyl]-1-methyl-1H-indol-5-ylcarbamate
Zafirlukast
Cyclopentyl (3-(2-methoxy-4-((o-tolylsulfonyl)carbamoyl)benzyl)-1-methyl-1H-indol-5-yl)carbamate
Accolate
cyclopentyl (1-methyl-3-{[2-(methyloxy)-4-({[(2-methylphenyl)sulfonyl]amino}carbonyl)phenyl]methyl}-1H-indol-5-yl)carbamate
Carbamic acid, N-[3-[[2-methoxy-4-[[[(2-methylphenyl)sulfonyl]amino]carbonyl]phenyl]methyl]-1-methyl-1H-indol-5-yl]-, cyclopentyl ester
MFCD00864775

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Melting Point ]:
139°C

[ Molecular Formula ]:
C₃₁H₃₃N₃O₆S

[ Molecular Weight ]:
575.675

[ Exact Mass ]:
575.208984

[ PSA ]:
131.09000

[ LogP ]:
6.15

[ Index of Refraction ]:
1.641

[ Storage condition ]:
Refrigerator

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Statements ]:
H413

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

2-Methylbenzene-1-sulfonamide
4-[[5-[[cyclopentyloxy)carbonyl]amino]-1-methylindol-3-yl]methyl]-3-methoxybenzoic acid
Methyl 4-(bromomethyl)-3-methoxybenzoate
4-[5-nitro-1H-indol-3-ylmethyl]-3-methoxy-benzoic acid methylester
Methyl-Benzoate,Zafirlukast,
5-Nitroindole
Cyclopentyl carbonochloridate
4-(5-Amino-1-methyl-1H-indol-3-ylmethyl)-3-methoxy-benzoic acid methyl ester
4-[[5-[[(Cyclopentyloxy)carbonyl]amino]-1-Methyl-1H-indol-3-yl]Methyl]-3-Methoxy-benzoic Acid Methyl Ester
1-Methyl-5-Nitroindole

DownStream

Articles

Novel strategy for biofilm inhibition by using small molecules targeting molecular chaperone DnaK.

Antimicrob. Agents Chemother. 59(1) , 633-41, (2014)

Biofilms are complex communities of microorganisms that attach to surfaces and are embedded in a self-produced extracellular matrix. Since these cells acquire increased tolerance against antimicrobial...

Rapid determination of canagliflozin in rat plasma by UHPLC-MS/MS using negative ionization mode to avoid adduct-ions formation.

Talanta 132 , 29-36, (2014)

Canagliflozin is the first sodium-glucose co-transporter-2 inhibitor, approved by the US Food and Drug Administration for the treatment of type 2 diabetes mellitus. In this study, a sensitive UHPLC-MS...

Volume-sensitive release of organic osmolytes in the human lung epithelial cell line A549: role of the 5-lipoxygenase.

Am. J. Physiol. Cell Physiol. 305(1) , C48-60, (2013)

Pathophysiological conditions challenge cell volume homeostasis and perturb cell volume regulatory mechanisms leading to alterations of cell metabolism, active transepithelial transport, cell migratio...

Zafirlukast-d7
Zafirlukast p-Tolyl Isomer
Zafirlukast m-Tolyl Isomer
Methyl-Benzoate,Zafirlukast,
Zafirlukast m-Tolyl Isomer-d7
Zafirlukast p-Tolyl Isomer-d7
3-(4-(Trifluoromethyl)benzyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine
3-Furan-3-yl-8-methyl-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine
(9,9-dimethyl-9H-fluoren-2-yl)pyridin-4-ylamine
5-Fluoro-1,2,3,4-tetrahydro-8-methoxy-1-isoquinolinecarboxylic acid
Methyl 2-((tert-butoxycarbonyl)amino)-3-(1H-indol-3-yl)-3-oxopropanoate
Benzenecarboximidamide, 2-[[(5-chloro-2-pyridinyl)thio]methyl]-5-fluoro-
5-bromo-6-fluoro-3-methylbenzo[d]oxazol-2(3H)-one
Methyl 2-benzyl-1H-imidazole-4-carboxylate
methyl 2-cyclohexyl-1H-imidazole-5-carboxylate
3-Piperidinecarbonitrile, 3-[(2-hydroxyethyl)amino]-1-(phenylmethyl)-

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