2,3,4,5-TETRAHYDRO-6(4-CHLOROPHENYL)-3(2H)-PYRIDAZINONE

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Names

[ CAS No. ]:
1079-73-8

[ Name ]:
2,3,4,5-TETRAHYDRO-6(4-CHLOROPHENYL)-3(2H)-PYRIDAZINONE

[Synonym ]:
6-(chloro)-2,3,4,5-tetrahydropyridazine-3-one
6-(4-chlorophenyl)-2,4,5-trihydropyridazin-3-one
6-(4-chlorphenyl)-4,5-dihydropyridazine-3(2H)-one
3-p-Chlorophenylpyridazin-6-one
6-(4-chloro-phenyl)-4,5-dihydro-2H-pyridazin-3-one
6-(4-chlorophenyl)-2,3,4,5-tetrahydropyridazin-3-one
3(2H)-Pyridazinone,4,5-dihydro-6-(4-chlorophenyl)
6-(p-chlorophenyl)-4,5-dihydro-3(2H)-pyridazinone
6-(4-chlorophenyl)-4,5-dihydropyridazin-3(2H)-one
6-(4-chlorophenyl)-4,5-dihydro-3(2H)-pyridazinone
6-(4-chlorophenyl)-4,5-dihydropyridazinone

Chemical & Physical Properties

[ Density]:
1.36g/cm3

[ Molecular Formula ]:
C10H9ClN2O

[ Molecular Weight ]:
208.64400

[ Exact Mass ]:
208.04000

[ PSA ]:
44.95000

[ LogP ]:
1.66560

[ Index of Refraction ]:
1.641

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UR6357000
CHEMICAL NAME :
3(2H)-Pyridazinone, 4,5-dihydro-6-(4-chlorophenyl)-
CAS REGISTRY NUMBER :
1079-73-8
BEILSTEIN REFERENCE NO. :
0163382
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C10-H9-Cl-N2-O
MOLECULAR WEIGHT :
208.66

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PJPPAA Polish Journal of Pharmacology and Pharmacy. (ARS Polona, POB 1001, 00-068 Warsaw 1, Poland) V.25- 1973- Volume(issue)/page/year: 28,537,1976

Safety Information

[ HS Code ]:
2933990090

Synthetic Route

Precursor & DownStream

Precursor

  • 4-(4-Chlorophenyl)-4-oxobutanoic acid
  • Chlorobenzene
  • methyl 4-(4-chlorophenyl)-4-oxo-butanoate
  • 2(3H)-Furanone,5-(4-chlorophenyl)-
  • 4-(3-chlorophenyl)-4-oxobutanoic acid

DownStream

  • 3-CHLORO-6-(4-CHLOROPHENYL)-PYRIDAZINE
  • 4-(4-Chlorophenyl)butanic acid
  • 6-(4-CHLOROPHENYL)-3(2H)PYRIDAZINONE
  • CHEMBRDG-BB 4000246

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%


Related Compounds

  • (2S)-1-[2-(dimethylamino)-4-methyl-1,3-thiazol-5-yl]propan-2-ol
  • 5-[2-(Trifluoromethyl)pyridin-3-yl]-1,2-oxazol-4-amine
  • 5-{3-[(Dimethylamino)methyl]-4-hydroxyphenyl}-1,3-oxazolidin-2-one
  • 1,1-Difluoro-2-methyl-4-(2,4,6-trimethylphenyl)butan-2-amine
  • 1-(2-Azidoethyl)-3-bromo-2,4-difluorobenzene
  • tert-butyl N-[3-(2,2-difluoroacetyl)-4-hydroxyphenyl]carbamate
  • 2-(5-methoxy-1,3-dimethyl-1H-pyrazol-4-yl)-1-methylpiperazine
  • (2,2-Dimethyl-1-{pyrazolo[1,5-a]pyridin-3-yl}cyclopropyl)methanol
  • O-{[1-(6-bromopyridin-3-yl)cyclopropyl]methyl}hydroxylamine
  • 1-(4-nitro-1H-pyrazol-3-yl)prop-2-en-1-one
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