Propylene carbonate

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Names

[ CAS No. ]:
108-32-7

[ Name ]:
Propylene carbonate

[Synonym ]:
1,2-Propanediol cyclic carbonate
1,3-Dioxolan-2-one, 4-methyl-
Propylene glycol cyclic carbonate
Carbonic acid cyclic 1,2-propylene ester
1, 3-Dioxolan-2-one, 4-methyl-
Cyclic propylene carbonate
PC-HP
Carbonic acid, cyclic propylene ether
Jeffsol PC
4-Methyl-1,3-dioxol-2-one
2-Oxo-4-methyl-1,3-dioxolane
1,2-Propanediol cyclic carbonate,4-Methyl-1,3-dioxolan-2-one
MFCD00005385
4-Methyl-1,3-dioxolan-2-one
4-Methyl-2-oxo-1,3-dioxolane
Propylene carbonate
Arconate 1000
EINECS 203-572-1

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
241.7±0.0 °C at 760 mmHg

[ Melting Point ]:
-49ºC

[ Molecular Formula ]:
C4H6O3

[ Molecular Weight ]:
102.089

[ Flash Point ]:
132.2±0.0 °C

[ Exact Mass ]:
102.031693

[ PSA ]:
35.53000

[ LogP ]:
-0.41

[ Vapour Pressure ]:
0.0±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.416

[ Stability ]:
Stable. Incompatible with strong oxidizing agents, acids, bases, reducing agents. Protect from contact with moist air or water.

[ Water Solubility ]:
240 g/L (20 ºC)

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H319

[ Precautionary Statements ]:
P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36

[ Safety Phrases ]:
26-37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
1

[ RTECS ]:
FF9650000

[ HS Code ]:
2932999099

Synthetic Route

Precursor & DownStream

Precursor

  • Propylene Glycol
  • carbon monoxide
  • Carbon dioxide
  • epoxypropane
  • Trimethylsulfoxonium iodide
  • ch3cho
  • Ethanol
  • 2H-oxete
  • phosgene
  • 3-Methyloxetane

DownStream

  • Dibutyl carbonate
  • 2,6-dimethyl-4-phenylmorpholine
  • N-(hydroxy-2-propyl)aniline
  • 1-anilinopropan-2-ol
  • N,N-BIS(2-HYDROXYPROPYL)ANILINE
  • 1-[N-(1-hydroxypropan-2-yl)anilino]propan-2-ol
  • Dibenzyl carbonate
  • Propylene Glycol
  • Ethyl carbonate

Customs

[ HS Code ]: 2932999099

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Transdermal delivery of curcumin via microemulsion.

Int. J. Pharm. 481(1-2) , 97-103, (2015)

The objective of this study was to evaluate the transdermal delivery potential of a new curcumin-containing microemulsion system. Three series of experiments were carried out to comprehend the system ...

A Systematic Study on Manufacturing of Prilled Microgels into Lipids for Oral Protein Delivery.

J. Pharm. Sci. 104 , 3351-65, (2015)

The development of novel systems with oral protein delivery as ultimate goal represents an important field of pharmaceutics. Prilling of protein-loaded polymeric solutions into lipid-based hardening b...

On prilling of hydrophilic microgels in lipid dispersions using mono-N-carboxymethyl chitosan for oral biologicals delivery.

J. Pharm. Sci. 103(11) , 3675-87, (2014)

Oral delivery of biologicals is a thriving field in pharmaceutics and the first challenge is to achieve a stable drug product. Interesting is prilling of a drug-containing polymeric solution as microg...


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Related Compounds

  • 1,3-propylene carbonate
  • (R)-Propylene Carbonate
  • (S)-Propylene Carbonate
  • polypropylene carbonate
  • Poly(propylene carbonate)
  • 1-butoxy-2,3-propylene carbonate