2-Amino-5-methyl-1,3,4-thiadiazole

Suppliers

Names

[ CAS No. ]:
108-33-8

[ Name ]:
2-Amino-5-methyl-1,3,4-thiadiazole

[Synonym ]:
MFCD00003110
EINECS 203-573-7
5-Methyl-1,3,4-thiadiazol-2-amine

Chemical & Physical Properties

[ Density]:
1.372 g/cm3

[ Boiling Point ]:
261.2ºC at 760 mmHg

[ Melting Point ]:
224-225 °C

[ Molecular Formula ]:
C3H5N3S

[ Molecular Weight ]:
115.15700

[ Flash Point ]:
111.8ºC

[ Exact Mass ]:
115.02000

[ PSA ]:
80.04000

[ LogP ]:
1.00990

[ Vapour Pressure ]:
6.12E-05mmHg at 25°C

[ Index of Refraction ]:
1.631

[ Storage condition ]:
Room temperature.

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XI3500000
CHEMICAL NAME :
1,3,4-Thiadiazole, 2-amino-5-methyl-
CAS REGISTRY NUMBER :
108-33-8
LAST UPDATED :
199504
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C3-H5-N3-S
MOLECULAR WEIGHT :
115.17
WISWESSER LINE NOTATION :
T5NN DSJ CZ E1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FRMCE8 Farmaco. (Societa Chimica Italiana, Corso Strada Nova, 86, Casella Postale 227, 27100 Pavia, Italy) V.44- 1989- Volume(issue)/page/year: 45,223,1990
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - quail
DOSE/DURATION :
>316 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EESADV Ecotoxicology and Environmental Safety. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1977- Volume(issue)/page/year: 6,149,1982 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7009 No. of Facilities: 4 (estimated) No. of Industries: 1 No. of Occupations: 16 No. of Employees: 1470 (estimated)

Safety Information

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S24/25-S37/39-S26

[ RTECS ]:
XI3500000

[ HS Code ]:
2934999090

Synthetic Route

Precursor & DownStream

Precursor

  • acetic acid
  • Thiosemicarbazide
  • Acetyl chloride
  • 2,3-DIMETHYLTHIAZOLINIUM IODIDE
  • BENZYL THIOACETIMIDATE HYDROCHLORIDE
  • Acetamide,N-(5-methyl-1,3,4-thiadiazol-2-yl)-
  • 2,3,4,4-tetramethyl-2-oxazolinium iodide
  • 2-Acetylhydrazinecarbothioamide
  • 5-imino-2-methyl-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-one

DownStream

  • Acetamide,N-[5-[2-(5-nitro-2-furanyl)ethenyl]-1,3,4-thiadiazol-2-yl]-
  • 1,3,4-Thiadiazole,2-methyl-5-nitro-
  • Urea,N-methyl-N'-(5-methyl-1,3,4-thiadiazol-2-yl)-
  • 2-Mercapto-5-methyl-1,3,4-thiadiazole
  • 2-Bromo-5-methyl-1,3,4-thiadiazole
  • 3-methyl-1-(5-methyl-1,3,4-thiadiazol-2-yl)-4-phenylpyrrolidine-2,5-dione
  • Acetamide,N-(5-methyl-1,3,4-thiadiazol-2-yl)-
  • Sulfamethizole
  • N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenecarboximidamide
  • Urea,(5-methyl-1,3,4-thiadiazol-2-yl)- (6CI,8CI,9CI)

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%


Related Compounds

  • 2-amino-5-methyl-1,3,4-thiadiazole
  • 2-AMINO-5-METHYL-1,3,4-THIADIAZOLE HCl
  • 2-AMINO-5-(3-METHYLPHENOXY) METHYL-1,3,4-THIADIAZOLE
  • N-[2-(5-methyl-1,3,4-thiadiazole-2-sulfonylamino)-ethyl]-glycine ethyl ester
  • Acetamide,N-(5-methyl-1,3,4-thiadiazol-2-yl)-
  • 5-Methyl-1,3,4,6,9b-pentaazaphenalen-2-ylamine
  • N-((1-(4-ethoxyphenyl)-1H-tetrazol-5-yl)methyl)-3,5-dimethoxybenzamide
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 1-Azaspiro[5.5]undecan-2-one
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • p-Tolylcarbodiimid
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • (2-Chloro-6-methyl-3-nitro-pyridin-4-yl)-(1-ethyl-propyl)-amine