4-Methyl-2-pyrimidinamine

Suppliers

Names

[ CAS No. ]:
108-52-1

[ Name ]:
4-Methyl-2-pyrimidinamine

[Synonym ]:
MFCD00006101
EINECS 203-591-5
2-Pyrimidinamine, 4-methyl-
4-Methylpyrimidin-2-Amine
2-Amino-4-methylpyrimidine
4-Methyl-2-pyrimidinamine

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
283.4±33.0 °C at 760 mmHg

[ Melting Point ]:
158-160 °C(lit.)

[ Molecular Formula ]:
C5H7N3

[ Molecular Weight ]:
109.129

[ Flash Point ]:
149.9±12.6 °C

[ Exact Mass ]:
109.063995

[ PSA ]:
51.80000

[ LogP ]:
0.24

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.582

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UV6485000
CHEMICAL NAME :
Pyrimidine, 2-amino-4-methyl-
CAS REGISTRY NUMBER :
108-52-1
BEILSTEIN REFERENCE NO. :
0108506
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C5-H7-N3
MOLECULAR WEIGHT :
109.15
WISWESSER LINE NOTATION :
T6N CNJ BZ D1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
730 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 211,367,1950

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
UV6485000

[ HS Code ]:
2933599090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 5-Bromo-4-methyl-2-pyrimidinamine
  • Bis(pinacolato)diboron
  • 4-(Trimethylsilyl)-3-butyn-2-one
  • Guanidine hydrochloride
  • 4-Chloro-6-methyl-2-pyrimidinamine
  • Carbonic acid-guanidine (1:2)
  • 3-Buten-2-one,3-(4-morpholinyl)-
  • Ethyl 2-amino-4-methylpyrimidine-5-carboxylate
  • 2-Dimethylaminomethylen-acetessigsaeureethylester
  • 2-amino-4-methylpyrimidine-5-carboxylic acid

DownStream

  • N,4-dimethylpyrimidin-2-amine
  • 4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-amine
  • 4-Methyl-2-(1-piperazinyl)pyrimidine
  • N-[4-[[(4-methyl-2-pyrimidinyl)amino]sulphonyl]phenyl]acetamide
  • 2-Bromo-4-methylpyrimidine
  • 2-Chloro-4-methylpyrimidine
  • Sulfamerazine
  • 5-Bromo-4-methyl-2-pyrimidinamine
  • 5-chloro-4-methylpyrimidin-2-amine

Customs

[ HS Code ]: 2933599090

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 5-Bromo-4-methyl-2-pyrimidinamine
  • 5-Chloro-4-methyl-2-pyrimidinamine
  • N-Hydroxy-4-methyl-2-pyrimidinamine
  • N-Cyclopropyl-4-methyl-2-pyrimidinamine
  • 5-(3,4-Dimethoxyphenyl)-4-methyl-2-pyrimidinamine
  • 5-(1,3-benzodioxol-5-yl)-4-methyl-2-pyrimidinamine
  • 1-[5-(Methoxymethyl)furan-2-yl]-2-methylpropan-2-amine
  • 1,4-Oxazepan-6-ol 2,2,2-trifluoroacetic acid
  • (2S)-2-amino-4-hydroxy-5,5-dimethylhexanoic acid
  • N-(2-bromo-2,2-difluoroethyl)-1-methyl-1H-indol-5-amine
  • 4-Hydroxy-2-formamido-4-methylhexanoic acid
  • 2-[2-Chloro-6-(propan-2-ylsulfanyl)phenyl]-2-fluoroethan-1-amine
  • 5-Fluoro-2,6-dimethylpyrimidine-4-carboxylic acid
  • 4-(1,1-Difluoroethyl)-2-fluorobenzoic acid
  • 2-[3-(Propan-2-yl)phenyl]cyclopropan-1-amine
  • 2-(4,5-Difluoro-2-methoxyphenyl)-3,3-difluoropropan-1-amine
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