Glutaric Anhydride

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Names

[ CAS No. ]:
108-55-4

[ Name ]:
Glutaric Anhydride

[Synonym ]:
2H-Pyran-2,6(3H)-dione, dihydro
2H-Pyran-2,6(3H)-dione, dihydro-
dihydro-3H-pyran-2,6-dione
Glutaric anhydride
Glutaric acid anhydride
Dihydro-2H-pyran-2,6(3H)-dione
Dihydro-pyran-2,6-dione
EINECS 203-593-6
MFCD00006679

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
287.0±0.0 °C at 760 mmHg

[ Melting Point ]:
50-55 °C(lit.)

[ Molecular Formula ]:
C5H6O3

[ Molecular Weight ]:
114.099

[ Flash Point ]:
120.9±15.9 °C

[ Exact Mass ]:
114.031693

[ PSA ]:
43.37000

[ LogP ]:
-0.92

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.463

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
hydrolysis

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
MA3850000
CHEMICAL NAME :
Glutaric anhydride
CAS REGISTRY NUMBER :
108-55-4
BEILSTEIN REFERENCE NO. :
0110051
LAST UPDATED :
199806
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C5-H6-O3
MOLECULAR WEIGHT :
114.11
WISWESSER LINE NOTATION :
T6VOVTJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
540 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Gastrointestinal - necrotic changes Liver - hepatitis (hepatocellular necrosis), diffuse
REFERENCE :
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 36(1,pt2),272,1997
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
1780 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H312-H315-H318-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R21/22;R36/37/38

[ Safety Phrases ]:
S26-S36/39-S36/37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
MA3850000

[ HS Code ]:
2917190090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • glutaryl dichloride
  • Glutaric acid
  • Acetylcyclopentanone
  • Ethanoic anhydride
  • glutaraldehyde
  • acetic acid
  • 1,5-Ethano-1H-1-benzazepin-2(3H)-one, 4,5-dihydro
  • (1,2-bis(diphenylphosphino)ethane)NiCH2CH2CH2COO
  • 1,1,3,3-tetraethyl propane-1,1,3,3-tetracarboxylate

DownStream

  • 1-BENZYL-3,4-DIHYDRO-1H-PYRIDIN-2-ONE
  • 5-(butylamino)-5-oxopentanoic acid
  • Pentanoic acid,5-[(6-amino-1,2,3,4-tetrahydro-1,3-dimethyl-2,4-dioxo-5-pyrimidinyl)amino]-5-oxo-
  • Pyrido[1,2-a]benzimidazol-1(2H)-one, 3,4-dihydro- (7CI,9CI)
  • 1-Benzyl-2,6-piperidinedione
  • N-Carbobenzoxy-4-aminobutyric Acid
  • 5-(Bis(2-hydroxyethyl)amino)-1-methyl-1H-benzimidazole-2-butanoic acid ethyl ester
  • 5-Oxononanoic acid
  • 5-naphthalen-2-yl-5-oxo-pentanoic acid
  • 3-(P-CHLOROBENZOYL)-BUTYRIC ACID

Customs

[ HS Code ]: 2917190090

[ Summary ]:
2917190090 acyclic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

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Related Compounds

  • Glutaric anhydride
  • Glutaric anhydride-d6
  • 3-ethylglutaric anhydride
  • 2-PHENYLGLUTARIC ANHYDRIDE
  • dimethylglutaric anhydride
  • Glutaric Anhydride-1,5-13C2
  • 4-[[(Z)-2-cyano-3-(2,5-dichloro-3-phenylimidazol-4-yl)prop-2-enoyl]amino]benzoic acid
  • Propyl 3-amino-2-naphthalenecarboxylate
  • 2-(6-fluoropyridin-3-yl)oxy-N-methylpropanamide
  • [(4-Bromo-2-fluorophenyl)methyl](pyridin-2-ylmethyl)amine
  • 2-{[(4-Bromo-2-fluorophenyl)methyl]amino}ethanol
  • 6,7-Dihydro-I+/--methylthieno[3,2-c]pyridine-5(4H)-propanenitrile
  • (3-Chlorophenyl)(4-(2,6-dimethoxypyrimidin-4-yl)piperazin-1-yl)methanone
  • (I+/-R)-I+/--[[[3-[[2-(3,5-Difluorophenoxy)ethyl]methylamino]propyl]amino]methyl]-6-methoxy-4-quinolinemethanol
  • 2-Bromo-N-(3-bromophenyl)-I+/--methylbenzenemethanamine
  • 4-(4-((3,4-Dichlorophenyl)sulfonyl)piperazin-1-yl)-2,6-dimethoxypyrimidine
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